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Promoter Capture Hi-C: High-resolution, Genome-wide Profiling of Promoter Interactions
Published on: June 28, 2018
Insulators and promoters: closer than we think
Jesse R Raab1, Rohinton T Kamakaka
1Department of Molecular Cell and Developmental Biology, Sinsheimer Labs, University of California, Santa Cruz, California 95064, USA.
Nature Reviews. Genetics
|May 6, 2010
Summary
Insulators, which regulate gene expression, share similarities with promoters. This study proposes they evolved from promoters, using related mechanisms for distinct gene-regulatory functions.
Area of Science:
- Molecular Biology
- Genetics
- Epigenetics
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