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An Ex vivo Assay to Study Candida albicans Hyphal Morphogenesis in the Gastrointestinal Tract
Published on: July 1, 2020
Infectious disease and cancer
1Department of Hematology/Oncology, Marshfield Clinic Research Foundation, Marshfield, WI 54449, USA. mazzaj@mfldclin.edu
Summary
Infectious disease agents are increasingly recognized as a cause of cancer, now accounting for approximately 20% of all malignancies. Understanding this link may lead to better cancer treatments.
Area of Science:
- Oncology
- Infectious Diseases
- Molecular Biology
- Genetics
Background:
- Malignant diseases remain a significant cause of human mortality globally.
- Recent advances in molecular biology and genetics have shed light on cancer etiology.
- Infectious disease agents are emerging as a critical factor in cancer development.
Purpose of the Study:
- To summarize cancers associated with or caused by infectious disease agents.
- To highlight the growing contribution of infectious agents to cancer incidence.
- To explore the potential for improved cancer treatment strategies based on this knowledge.
Main Methods:
- Review of scientific literature linking infectious agents to specific malignancies.
- Analysis of epidemiological data on cancer incidence attributed to infections.
- Synthesis of current understanding of molecular mechanisms involved.
Main Results:
- Infectious disease agents are linked to a growing number of cancers.
- Approximately 20% of all human cancers are now associated with specific infectious agents.
- Specific examples of infectious agents and their associated cancers are identified.
Conclusions:
- Infectious agents play a substantial role in the global cancer burden.
- Further research into the infectious causes of cancer is warranted.
- Translating this knowledge into novel therapeutic approaches holds promise for cancer treatment.
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