[Paraarticular Ossifications of Total Endoprostheses of the Hip Joint Part II: Effect of Indomethacin on their Genesis and Development.]

In the submitted paper the authors give an account on the use of Indomethacin in the prevention of paraarticular ossifications after implantation of a TEP of the hip joint, and on its effect of the development of these ossifications. This involves in particular inhibition of prostaglandin synthesis and partly also an antiphlogistic effect. The authors describe also their own observations regarding the effect of Indomethacin on the genesis and development of paraarticular ossifications. In the final evaluation they point out that Indomethacin does not reduce the incidence of paraarticular ossifications after implantation of TEP of the hip joint but contributes to the diminution of the final extent of ossification and thus has a positive effect on the final results of surgery. Key words: Indomethacin, paraarticular ossifications.