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Lysosomal Rag-ulation of mTOR complex 1 activity.

Robert T Abraham1

  • 1Center for Integrative Biology and Biotherapeutics, Pfizer Biopharmaceuticals, 401 N. Middletown Road, Pearl River, NY 10965, USA.

Cell Metabolism
|May 7, 2010
PubMed
Summary

Amino acid sensing activates mTORC1, a key regulator of cell metabolism and growth. Researchers discovered a lysosomal super-complex essential for this amino acid-dependent mTORC1 activation.

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