Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Jun 13, 2026

Updated Protocol for the Assembly and Use of the Minibioreactor Array (MBRA)
09:38

Updated Protocol for the Assembly and Use of the Minibioreactor Array (MBRA)

Published on: September 5, 2025

Modified bio-Bentall procedure: 10-year experience.

Paul P Urbanski1, Nico Heinz, Xiaochin Zhan

  • 1Cardiovascular Clinic Bad Neustadt, Bad Neustadt, Germany. p.urbanski@kardiochirurg.de

European Journal of Cardio-Thoracic Surgery : Official Journal of the European Association for Cardio-Thoracic Surgery
|May 7, 2010
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Repair of Asymmetric Bicuspid Aortic Valve Using Tricuspidation with CardioCel.

Interdisciplinary cardiovascular and thoracic surgery·2026
Same author

Annuloplasty for narrowing of the aortic annulus.

European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery·2025
Same author

A Cross-Sectoral Telemedicine Network (sekTOR-HF) for Patients with Heart Failure.

Journal of clinical medicine·2025
Same author

Aortic root repair using reimplantation or remodelling with and without an annuloplasty: a need for randomized studies.

European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery·2025
Same author

Aortic valve reconstruction with CardioCel: Midterm Results.

European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery·2025
Same author

Outcomes of RDAVR with Coronary Revascularization: 3-year Results from the German INCA Registry.

The Thoracic and cardiovascular surgeon·2025

This study shows that a modified composite graft for aortic root replacement allows for easier biological valve replacement if needed. This technique offers good outcomes and simplifies future interventions for patients.

Area of Science:

  • Cardiovascular Surgery
  • Biomaterials Engineering
  • Prosthetic Valve Technology

Background:

  • Biological aortic valve conduits are seldom used due to concerns about structural valve deterioration necessitating complex reoperations.
  • Existing methods for aortic root replacement with biological valves pose challenges for future valve exchange.

Purpose of the Study:

  • To assess the 10-year efficacy of a modified composite graft for aortic root replacement.
  • To evaluate a novel graft design enabling in-situ biological valve prosthesis replacement without disturbing coronary ostia.

Main Methods:

  • A retrospective analysis of 182 consecutive patients undergoing aortic root replacement with self-assembled composite grafts from 1998 to 2008.
  • The modified graft houses a biological valve prosthesis within a vascular tube, facilitating isolated valve replacement.

More Related Videos

Biobank for Translational Medicine: Standard Operating Procedures for Optimal Sample Management
08:01

Biobank for Translational Medicine: Standard Operating Procedures for Optimal Sample Management

Published on: November 30, 2022

Related Experiment Videos

Last Updated: Jun 13, 2026

Updated Protocol for the Assembly and Use of the Minibioreactor Array (MBRA)
09:38

Updated Protocol for the Assembly and Use of the Minibioreactor Array (MBRA)

Published on: September 5, 2025

Biobank for Translational Medicine: Standard Operating Procedures for Optimal Sample Management
08:01

Biobank for Translational Medicine: Standard Operating Procedures for Optimal Sample Management

Published on: November 30, 2022

  • Prospective collection of perioperative data, including indications for surgery and patient outcomes.

    • Main Results:

    • The technique allowed for significant valve oversizing in 30 patients with smaller annuli.
    • Low rates of re-operation for bleeding (4.4%) and no blood transfusions required for 37.9% of patients.
    • Overall survival was 74.2% at a mean follow-up of 4 years, with a linearized death rate comparable to control populations. Only one patient required re-operation for valve deterioration, which was easily performed.

    Conclusions:

    • The modified aortic composite graft with an internal biological valve offers feasible valve oversizing and excellent hemostatic properties.
    • This design simplifies valve prosthesis replacement in cases of deterioration, making it a recommendable option, particularly for younger patients.