Related Experiment Video
Updated: Jun 13, 2026

High-Temperature and High-Pressure In situ Magic Angle Spinning Nuclear Magnetic Resonance Spectroscopy
Published on: October 9, 2020
Transformative effects of higher magnetic field in Fourier transform ion cyclotron resonance mass spectrometry
N Murat Karabacak1, Michael L Easterling, Nathalie Y R Agar
1Department of Chemistry and Volen Center for Complex Systems, Brandeis University, Waltham, MA 02454, USA.
Abstract:
The relationship of magnetic field strength and Fourier transform ion cyclotron resonance mass spectrometry performance was tested using three instruments with the same design but different fields of 4.7, 7, and 9.4 tesla. We found that the theoretically predicted "transformative" effects of magnetic field are indeed observed experimentally. The most striking effects were that mass accuracy demonstrated approximately second to third order improvement with the magnetic field, depending upon the charge state of the analyte, and that peak splitting, which prohibited automated data analysis at 4.7 T, was not observed at 9.4 T.
Related Concept Videos
Mass Analyzers: Overview
Magnetic Fields
A magnetic field is defined by the force that a charged particle experiences...
Atomic Nuclei: Magnetic Resonance
Mass Analyzers: Common Types
Mass Spectrometers
π Electron Effects on Chemical Shift: Overview

