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Updated: Jun 13, 2026

Computational Prediction of Amino Acid Preferences of Potentially Multispecific Peptide-Binding Domains Involved in Protein-Protein Interactions
06:50

Computational Prediction of Amino Acid Preferences of Potentially Multispecific Peptide-Binding Domains Involved in Protein-Protein Interactions

Published on: January 26, 2024

HotPoint: hot spot prediction server for protein interfaces

Nurcan Tuncbag1, Ozlem Keskin, Attila Gursoy

  • 1Center for Computational Biology and Bioinformatics, and College of Engineering, Koc University, Rumelifeneri Yolu, 34450 Sariyer Istanbul, Turkey.

Nucleic Acids Research
|May 7, 2010
PubMed

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Protein-Protein Interfaces02:04

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Conserved Binding Sites

Many proteins’ biological role depends on their interactions with their ligands, small molecules that bind to specific locations on the protein known as ligand-binding sites. Ligand-binding sites are often conserved among homologous proteins as these sites are critical for protein function.
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Conserved Binding Sites01:49

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Ligand Binding Sites

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