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Updated: Jun 13, 2026

Preparation of Rat Oligodendrocyte Progenitor Cultures and Quantification of Oligodendrogenesis Using Dual-infrared Fluorescence Scanning
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Preparation of Rat Oligodendrocyte Progenitor Cultures and Quantification of Oligodendrogenesis Using Dual-infrared Fluorescence Scanning

Published on: February 17, 2016

Multiple kinase pathways regulate voltage-dependent Ca2+ influx and migration in oligodendrocyte precursor cells.

Pablo M Paez1, Daniel J Fulton, Vilma Spreur

  • 1Semel Institute for Neuroscience and Human Behavior, David Geffen School of Medicine at UCLA, Los Angeles, California 90095, USA.

The Journal of Neuroscience : the Official Journal of the Society for Neuroscience
|May 7, 2010
PubMed
Summary

Voltage-operated Ca(2+) channels (VOCCs) are crucial for oligodendrocyte progenitor cell (OPC) development. Protein kinase C (PKC) and tyrosine kinases (TKs) enhance VOCC activity, while protein kinase A (PKA) inhibits it, impacting OPC migration and morphology.

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