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Related Experiment Video

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Separating Beads and Cells in Multi-channel Microfluidic Devices Using Dielectrophoresis and Laminar Flow

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Flow field effect transistors with polarisable interface for EOF tunable microfluidic separation devices.

A Plecis¹, J Tazid, A Pallandre

¹Laboratoire de Photonique et de Nanostructures - CNRS UPR20, route de Nozay, 91460, Marcoussis, France. adrien.plecis@lpn.cnrs.fr

|May 7, 2010

Summary

Researchers developed a method to control zeta potential in microchannels using electrically polarisable interfaces. This technique enables precise electro-osmotic flow control for advanced separation applications.

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Area of Science:

Electrochemistry
Microfluidics
Materials Science

Background:

Controlling zeta potential is crucial for microfluidic applications.
Conventional methods face limitations in electrokinetic separation.
Electrically polarisable interfaces offer a novel approach.

Purpose of the Study:

To propose and validate a method for controlling zeta potential in microchannels.
To investigate the use of conducting layers with large potential windows.
To demonstrate the potential for developing new electrokinetic devices.

Main Methods:

Utilizing conducting layers (SiC, Al, CN(x)) on glass surfaces.
Integrating these interfaces into glass-PDMS-glass microfluidic devices.
Measuring electro-osmotic flow using a microfluidic Wheatstone Bridge.

Main Results:

Demonstrated tunable zeta potential without detrimental faradic reactions.
Experimental electro-osmotic flow measurements agreed with 1D modeling.
Achieved electro-osmotic flow control at high pH values.

Conclusions:

The proposed method effectively controls zeta potential in microchannels.
Developed devices show promise as Polarisable Interface Flow-Field Effect Transistors (PI-FFETs).
This approach can overcome limitations of conventional Metal-Isolator-Electrolyte systems for separation.