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EPONYM. Sweet syndrome.

Mi Jin Kim¹, Yon Ho Choe

¹Department of Pediatrics, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50 Irwon-dong, Gangnam-gu, Seoul 135-710, South Korea.

European Journal of Pediatrics

|May 7, 2010

Summary

This summary is machine-generated.

Sweet syndrome, or acute febrile neutrophilic dermatosis, presents as inflammatory skin lesions. Certain medications can trigger this rare condition in children, with six cases reported to date.

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Area of Science:

Dermatology
Pediatrics
Pharmacology

Background:

Sweet syndrome, also known as acute febrile neutrophilic dermatosis, is an inflammatory condition.
It is characterized by painful, red nodules or papules.
It is associated with infections, malignancies, connective tissue diseases, or drug exposure.

Observation:

Drug-induced Sweet syndrome is a rare but recognized adverse drug reaction.
In adults, granulocyte colony-stimulating factor, all-trans-retinoic acid, and other drugs are implicated.
In pediatric patients, granulocyte colony-stimulating factor, all-trans-retinoic acid, trimethoprim-sulfamethoxazole, and azathioprine have been identified as potential causes.

Findings:

This report includes a case of drug-induced Sweet syndrome in a child.
A total of six pediatric cases, including this one, have been documented in the literature.
The abstract highlights specific medications linked to Sweet syndrome in pediatric populations.

Implications:

Increased awareness of drug-induced Sweet syndrome in children is crucial for timely diagnosis and management.
Identifying causative agents is essential for preventing recurrence.
Further research may elucidate the mechanisms underlying drug-induced Sweet syndrome in pediatric patients.