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Somatosensory dysfunction in cystic fibrosis.
1Department of Neurosciences, University of California, San Diego.
European Neurology
|January 1, 1991
Summary
Cystic fibrosis patients show delayed nerve signals in the somatosensory system. This study used posterior tibial somatosensory evoked potentials to confirm neurological involvement in cystic fibrosis.
Area of Science:
- Neuroscience
- Medical Physiology
Background:
- Cystic fibrosis is a genetic disorder affecting multiple organs.
- Previous research suggests potential neurological complications in cystic fibrosis patients.
Purpose of the Study:
- To investigate the integrity of the somatosensory system in cystic fibrosis patients.
- To assess for delays in nerve signal transmission using electrophysiological methods.
Main Methods:
- Posterior tibial somatosensory evoked potentials (SEPs) were recorded.
- SEPs were measured in a cohort of cystic fibrosis patients and age-matched healthy controls.
Main Results:
- A statistically significant delay was observed in the lumbar potential.
- Early scalp potentials exhibited more pronounced delays in cystic fibrosis patients compared to controls.
Conclusions:
- The findings indicate a demonstrable involvement of the somatosensory nervous system in cystic fibrosis.
- Electrophysiological evidence supports earlier pathological findings of somatosensory system dysfunction.