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Predicting Amputation using Local Circulating Mononuclear Progenitor Cells in Angioplasty-treated Patients with Critical Limb Ischemia
Published on: September 22, 2020
Phaeochromocytoma-associated critical peripheral ischaemia
D Lutchman1, S Buchholz, C Keightley
1Department of Internal Medicine, Nambour General Hospital, Nambour, Queensland, Austrlia.
Internal Medicine Journal
|May 8, 2010
Summary
Catecholamine toxicity from phaeochromocytoma can cause limb ischaemia. A case of a patient experiencing severe peripheral ischaemia, gangrene, and limb amputation due to an adrenal gland phaeochromocytoma is presented.
Area of Science:
- Endocrinology
- Vascular Surgery
Background:
- Phacochromocytoma, a rare neuroendocrine tumor, can secrete excessive catecholamines.
- Catecholamine excess is a known cause of cardiovascular complications.
Observation:
- A middle-aged female presented with severe subacute peripheral limb ischaemia and gangrene.
- The patient ultimately required amputation of all four distal limbs.
Findings:
- The patient's condition was attributed to a large, non-metastatic left adrenal gland phaeochromocytoma.
- This case highlights limb ischaemia as an exceptional complication of phaeochromocytoma.
Implications:
- Early recognition of phaeochromocytoma is crucial in patients with unexplained peripheral ischaemia.
- Understanding this rare complication can guide diagnostic and therapeutic strategies in vascular and endocrine emergencies.
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