Related Experiment Video
Updated: Jun 13, 2026

CUBIC Protocol Visualizes Protein Expression at Single Cell Resolution in Whole Mount Skin Preparations
Published on: August 4, 2016
How to take skin biopsies for epidermolysis bullosa
Lizbeth Ruth A Intong1, Dédée F Murrell
1Department of Dermatology, St George Hospital, Kogarah, Sydney, NSW, Australia.
Abstract:
The definitive diagnosis of inherited epidermolysis bullosa is best made with positive immunofluorescence antigenic mapping, transmission electron microscopy, and epidermolysis bullosa-related monoclonal antibody studies. However, immunofluorescence microscopy is faster and easier as compared with electron microscopy for subtyping epidermolysis bullosa. The severity of the disease varies with the structural protein involved. A proper diagnosis should be made as soon as possible, and skin biopsies help with diagnosis. This article describes the technique of skin biopsy.
Related Concept Videos
Clinical Applications of Epidermal Stem Cells
Skin Cancer
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...

