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Updated: Jun 13, 2026

Surgical Porcine Model of Chronic Myocardial Ischemia Treated by Exosome-laden Collagen Patch and Off-pump Coronary Artery Bypass Graft
Published on: September 15, 2023
Anaortic, total-arterial, off-pump coronary artery bypass surgery: how to do it
Michael P Vallely1, Tristan D Yan, J James B Edelman
1Cardiothoracic Surgical Unit, Royal Prince Alfred Hospital, Sydney, Australia. michael.vallely@bigpond.com
Abstract:
Several large series have demonstrated that performing off-pump coronary artery bypass surgery without manipulating the ascending aorta (anaortic) utilising all-arterial grafts provides superior protection against neurological injury. Recent series comparing percutaneous coronary intervention (PCI) with surgical revascularisation have demonstrated superior results for surgery over PCI. However, a significant criticism of coronary artery surgery remains the higher incidence of neurological injury when compared to PCI. We present a simple and reproducible technique for anaortic, total-arterial off-pump coronary artery revascularisation.
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