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Rotavirus vaccination coverage among infants aged 5 months - immunization information system sentinel sites, United
Insights
Rotavirus vaccination coverage in U.S. infants increased after introduction but remains lower than DTaP and PCV7 vaccines. Addressing barriers is crucial to prevent severe rotavirus disease.
Area of Science:
- Pediatric Infectious Diseases
- Vaccinology
- Public Health Surveillance
Background:
- Routine rotavirus vaccination (RV) for U.S. infants was recommended in 2006 and updated in 2008 with a second vaccine option.
- The maximum age for the first dose of either rotavirus vaccine is 14 weeks and 6 days.
Purpose of the Study:
- To assess trends in rotavirus vaccine coverage among U.S. infants from June 2006 to June 2009.
- To compare rotavirus vaccine coverage with diphtheria, tetanus, acellular pertussis (DTaP) and pneumococcal conjugate vaccine (PCV7) in 2009.
Main Methods:
- Analysis of data from Immunization Information System (IIS) sentinel sites.
- Assessment of coverage for at least one dose of rotavirus vaccine among 5-month-old infants.
- Comparison of rotavirus vaccine coverage with DTaP and PCV7 coverage in the second quarter of 2009.
Main Results:
- Rotavirus vaccine coverage increased post-introduction, averaging 72% at eight IIS sentinel sites by June 2009.
- Coverage with at least one dose of rotavirus vaccine was 13% lower than DTaP and PCV7 vaccines among 5-month-old infants.
- Lower rotavirus vaccine uptake may be due to new vaccine dynamics or specific barriers.
Conclusions:
- While rotavirus vaccination rates are increasing, they lag behind other routine infant vaccines.
- Identifying and mitigating barriers to rotavirus vaccination is essential for improving coverage.
- Enhanced education on rotavirus vaccine benefits can help prevent severe rotavirus disease.
Abstract:
In February 2006, the Advisory Committee on Immunization Practices (ACIP) recommended routine vaccination of all U.S. infants with 3 doses of a pentavalent rotavirus vaccine administered at ages 2, 4, and 6 months. In June 2008, ACIP updated its recommendations to include use of a second rotavirus vaccine, a 2-dose monovalent vaccine, administered at ages 2 and 4 months. The maximum age for the first dose of either rotavirus vaccine (RV) is 14 weeks and 6 days. CDC recently analyzed data from Immunization Information System (IIS) sentinel sites 1) to assess trends in coverage with >or=1 dose of RV during June 2006--June 2009 among infants aged 5 months and 2) to compare RV coverage in the second quarter of 2009 with that of two other routinely-recommended vaccines for U.S. infants: diphtheria, tetanus, and acellular pertussis (DTaP) vaccine, and 7-valent pneumococcal conjugate vaccine (PCV7). RV coverage increased following vaccine introduction and, in June 2009, averaged 72% at the eight currently participating IIS sentinel sites. However, >or=1 dose RV coverage among infants aged 5 months was 13% lower than the average coverage with >or=1 dose of DTaP and PCV7 at these same sites. Lower RV coverage could reflect typical new-vaccine coverage dynamics, the presence of RV-specific barriers, or both. Identifying and reducing barriers to vaccination and educating parents and providers about the health benefits of rotavirus vaccination should increase coverage and help prevent severe rotavirus disease.
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