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Updated: Jun 13, 2026

A Murine Model of Fetal Exposure to Maternal Inflammation to Study the Effects of Acute Chorioamnionitis on Newborn Intestinal Development
Published on: June 24, 2020
[Study of factors associated with subclinical chorioamnionitis in term pregnancy]
Wen-ying Zhang1, Ling Zhou, Yan-li Dang
1Department of Obstetrics & Gynecology, No. 306 Hospital of PLA, Beijing 100101, China. wyzhang1@yahoo.com.cn
Objective:
To investigate the effects of various factors upon subclinical chorioamnionitis (SCCAS) during pregnancy and delivery.
Methods:
A total of 796 cases of pregnancy in full-term birth at our hospital from December 2006 to December 2008 were reviewed. The data of maternal age, gravidity, parity, gestational age, prenatal care, history of vaginitis, premature rupture of membranes, occupation, educational status and delivery mode were recorded. And then the relationship between one of them and chorioamniotis were analyzed by chi(2) test.
Results:
The overall incidence of SCCAS was 39.95% in full-term birth. The pregnant women, who had no prenatal care or no occupation, or had a history of vaginitis or premature rupture of membranes, were found to have a higher incidence (P < 0.05 or P < 0.01). However, there were no statistical significance (P > 0.05) between SCCAS and other seven factors, such as gravida age, gravidity, parity, gestational age, educational status, delivery mode and living conditions.
Conclusion:
Women with full-term birth, even in the absence of symptoms, may have already suffered from acute or chronic chorioamnionitis. The incidence is associated with prenatal care, history of vaginitis and premature rupture of membranes.
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