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Updated: Jun 13, 2026
10:37
Deep Proteome Profiling by Isobaric Labeling, Extensive Liquid Chromatography, Mass Spectrometry, and Software-assisted Quantification
Published on: November 15, 2017
Nanotechniques in proteomics: current status, promises and challenges
Sandipan Ray1, Harini Chandra, Sanjeeva Srivastava
1Department of Biosciences and Bioengineering, Indian Institute of Technology Bombay, Powai, Mumbai 400076, India.
Biosensors & Bioelectronics
|May 11, 2010
Summary
Nanotechnology enhances proteomics by enabling sensitive detection of low-abundance proteins. Further research is needed on nanotoxicity and biocompatibility for in vivo applications.
Area of Science:
- Proteomics
- Nanotechnology
- Biotechnology
Background:
- Proteomics research demands high-throughput technologies for studying complex proteins.
- Traditional methods are being augmented by nanotechnology for enhanced protein analysis.
Purpose of the Study:
- To review the current status and advances in nanotechniques for proteomics.
- To highlight the prospects, merits, and challenges of nanoproteomics.
Main Methods:
- Review of nanotechniques including carbon nanotubes, nanowires, quantum dots, and gold nanoparticles.
- Focus on increasing sensitivity and improving biocompatibility in proteomics.
Main Results:
- Nanotechniques offer high sensitivity, real-time measurements, and improved reproducibility for protein detection.
- Nanoparticles like carbon nanotubes, nanowires, quantum dots, and gold are promising for nanoproteomics.
Conclusions:
- Nanoproteomics presents a powerful platform for sensitive and rapid protein detection.
- Further investigation into the toxicity and biocompatibility of nanotechniques is crucial for in vivo applications.
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