Related Experiment Video
Updated: Jun 13, 2026

Structured Approach to Colonoscopy Technique Optimization: A Single-Center Experience with Novice Endoscopists
Published on: July 11, 2025
CT colonography: perforation rates and potential radiation risks
A Berrington de Gonzalez1, Kwang Pyo Kim, Judy Yee
1Division of Cancer Epidemiology & Genetics, Radiation Epidemiology Branch, National Cancer Institute, 6120 Executive Boulevard, Bethesda, MD 20892, USA. berringtona@mail.nih.gov
Abstract:
Computed tomographic colonography (CTC) has emerged as an alternative screening tool for colorectal cancer due to the potential to provide good efficacy combined with greater acceptability than optical colonoscopy or fecal occult blood testing. However, some organizations have raised concerns about the potential harms, including perforation rates and radiation-related cancer risks, and have not recommended that it currently be used as a screening tool in the general population in the US. In this article the authors review the current evidence for these potential harms from CTC and compare them to the potential harms from the alternatives including colonoscopy and double-contrast barium enema.
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