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Updated: Jun 13, 2026

Robotic Enucleation of Esophageal Leiomyoma
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Robotic Enucleation of Esophageal Leiomyoma

Published on: February 20, 2026

Understanding cellular leiomyomas: a case-control study.

F Andrei Taran1, Amy L Weaver, Bobbie S Gostout

  • 1Division of Reproductive Endocrinology, Department of Obstetrics and Gynecology, Mayo Clinic, Rochester, MN 55905, USA.

American Journal of Obstetrics and Gynecology
|May 11, 2010
PubMed
Summary
This summary is machine-generated.

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Cellular leiomyomas (CLs) present distinct clinical features compared to typical uterine leiomyomas (ULs). This finding suggests CLs may share some characteristics with uterine leiomyosarcomas.

Area of Science:

  • Gynecologic Oncology
  • Pathology
  • Reproductive Medicine

Background:

  • Cellular leiomyomas (CLs) can exhibit clinical or genetic similarities to uterine leiomyosarcomas.
  • Distinguishing CLs from typical uterine leiomyomas (ULs) is clinically important.

Purpose of the Study:

  • To investigate the clinical differences between cellular leiomyomas (CLs) and typical uterine leiomyomas (ULs).

Main Methods:

  • A case-control study comparing 99 women with CLs to 198 women with ULs.
  • Matched controls based on surgical procedures between 1989 and 2008.
  • Review of hospital and ambulatory medical records.

Main Results:

  • Women with CLs were more likely to undergo surgery for enlarging leiomyomas.

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  • Concomitant endometriosis or adenomyosis was less frequent in women with CLs.
  • Uteri with CLs tended to have larger, fewer leiomyomas than controls.

    • Conclusions:

    • Cellular leiomyomas (CLs) possess a distinct clinical phenotype compared to typical uterine leiomyomas (ULs).
    • CLs share certain clinical characteristics with uterine leiomyosarcomas, warranting further investigation.