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Updated: Jun 13, 2026
Teratoma Generation in the Testis Capsule
Published on: November 7, 2011
A call to standardize teratoma assays used to define human pluripotent cell lines
Franz-Josef Müller1, Johanna Goldmann, Peter Löser
1Department of Chemical Physiology, The Scripps Research Institute, La Jolla, CA 92037, USA. fj.mueller@zip.kiel.de
Abstract:
The teratoma assay is the gold standard for documenting pluripotency of human stem cells. However, reports of new human ESC and iPSC lines vary widely in both methods and analysis of teratoma data. We call for consensus standards to be established to make this assay worthy of its "golden" status.
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