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Related Concept Videos

Dosage Regimens: Designs and Approaches01:28

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Designing a dosage regimen, which refers to the manner of drug administration, is a complex process involving the selection of drug dose, route, and frequency. This process is underpinned by pharmacokinetic parameters derived from tests and population averages. These parameters are then tailored to patient-specific variables such as diagnosis, demographics, and allergy status. Once therapy commences, therapeutic response monitoring is critical and achieved through clinical and physical...
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Dosage Regimen: Individualization01:24

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Individualization in dosing regimens is the customization of medication doses for individual patients. Its necessity arises from the goal of maximizing therapeutic benefits while minimizing risks. This approach is pivotal because human responses to drugs can vary widely; what is effective for one person may be inadequate or excessive for another. Interpatient (intersubject) variability refers to differences in drug responses between individuals, while intrapatient (intrasubject) variability...
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Elderly individuals encompass a diverse population with varying degrees of age-related physiological changes. Defining the elderly presents challenges, as the geriatric population is often arbitrarily categorized as individuals older than 65. However, many individuals in this group lead active and healthy lives, with an increasing number surpassing 85 years and falling into the older elderly category. Physiological changes associated with aging impact performance capacity and homeostatic...
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Drug Therapy01:28

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The advent of drug therapy has profoundly shaped modern mental health care, providing targeted treatments for a range of psychological disorders. Psychotherapeutic drugs, classified into antianxiety, antidepressant, and antipsychotic medications, address symptoms across anxiety disorders, mood disorders, and schizophrenia. While these medications have transformed patient outcomes, they require careful management due to their potential side effects and limitations.
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Drug Dosage Regimen: Overview01:15

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A drug dosage regimen describes the specific instructions and schedule for administering a drug to a patient. It considers factors such as drug dosage, frequency, route of administration, and duration of treatment. Designing an appropriate dosage regimen for a patient aims to achieve a target drug concentration at the site of action.
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Drug dependence, abuse, and addiction are complex phenomena that can precipitate various abnormal states. Physical dependence refers to a state of pharmacological adaptation to a drug. This adaptation often results in tolerance—a reduced response to the drug after repeated administrations. When the drug use is abruptly stopped, withdrawal symptoms occur due to the body's need to readjust from the pharmacologically induced imbalance. However, tolerance and withdrawal symptoms do not...
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Medication adherence: pharmacist perspective.

Joseph Bubalo1, Roger K Clark, Susie S Jiing

  • 1OHSU Pharmacy Services, Oregon Health and Science University, SW Sam Jackson Park Rd., Portland, OR 97239, USA. bubaloj@ohsu.edu

Journal of the American Pharmacists Association : Japha
|May 11, 2010
PubMed
Summary
This summary is machine-generated.

Pharmacists can improve patient medication adherence by discussing barriers and implementing personalized interventions. Addressing challenges in medication adherence is key to patient treatment success.

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Area of Science:

  • Pharmacy Practice
  • Patient Adherence Research

Background:

  • Medication adherence is a significant challenge in healthcare.
  • Nonadherence impacts treatment outcomes and healthcare costs.

Purpose of the Study:

  • To provide a comprehensive review of medication adherence challenges.
  • To outline effective solutions and intervention strategies for pharmacists.

Main Methods:

  • Systematic literature search of PubMed and Medline databases.
  • Selection of English-language review articles on medication adherence.
  • Analysis of 55 selected publications and 15 additional case examples.

Main Results:

  • Identified common barriers to medication adherence related to treatment and conditions.
  • Reviewed various methods for monitoring patient adherence.
  • Evaluated the effectiveness of multiple adherence intervention strategies.

Conclusions:

  • Nonadherence stems from diverse causes, requiring tailored approaches.
  • Open pharmacist-patient dialogue is crucial for identifying adherence barriers.
  • Multifaceted, personalized interventions enhance patient adherence to medical advice.