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Updated: Jun 13, 2026

Monitoring the Wall Mechanics During Stent Deployment in a Vessel
Published on: May 8, 2012
Intriguing peri-strut low-intensity area detected by optical coherence tomography after coronary stent deployment
Tomohiko Teramoto1, Fumiaki Ikeno, Hiromasa Otake
1Department of Cardiovascular Medicine, Stanford University, Stanford, CA, USA.
Background:
Although peri-strut low-intensity area (PLIA) is frequently observed on post-stenting optical coherence tomography (OCT) images, the histology associated with PLIA is undocumented.
Methods And Results:
The 36 porcine coronary lesions treated with bare-metal (BMS: n=16) or drug-eluting (DES: n=20) stents were assessed by OCT and histology at 28 days. DES showed a significantly higher incidence of PLIA than BMS. Also, +PLIA stents had greater neointima than PLIA stents. Histological analysis revealed the existence of fibrinoid and proteoglycans at the site of PLIA.
Conclusions:
PLIA might be represented by the presence of fibrinoid and proteoglycans, and associated with neointimal proliferation after stenting.
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