Related Experiment Video

Updated: Jun 13, 2026

RhoC GTPase Activation Assay
09:58

RhoC GTPase Activation Assay

Published on: August 22, 2010

A transcriptional cross-talk between RhoA and c-Myc inhibits the RhoA/Rock-dependent cytoskeleton

V Sauzeau1, I M Berenjeno, C Citterio

  • 1Centro de Investigación del Cáncer, CSIC-University of Salamanca, Campus Unamuno, Salamanca, Spain.

Oncogene
|May 11, 2010
PubMed
Summary

The GTPase RhoA and transcriptional factor c-Myc form a novel feedback loop impacting cytoskeletal dynamics. This interaction influences cell growth and cancer development by regulating F-actin, Cdc42, and integrins.

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