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Updated: Jun 13, 2026

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Assembly, Tuning and Use of an Apertureless Near Field Infrared Microscope for Protein Imaging
Published on: November 25, 2009
Abstract:
Investigating the source of a round patch of light in a dark hallway led to discovery of the pinhead mirror, a reflecting analog of the pinhole lens. Some pinhead mirrors were made and tested. The pinhead mirror's imaging characteristics appear to be similar to those of the pinhole lens.
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In optical microscopy, the specimen to be viewed is placed on a glass slide and clipped on the stage...
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The early pioneers of microscopy opened a window into the invisible world of microorganisms. In 1830, Joseph Jackson Lister created an essentially modern light microscope. The 20th century saw the development of microscopes that leveraged nonvisible light, such as fluorescence microscopy that uses an ultraviolet light source and electron microscopy that uses short-wavelength electron beams. These advances significantly improved magnification, image resolution, and contrast. By comparison, the...

