Related Experiment Video
Updated: Jun 13, 2026

Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration
Published on: May 26, 2023
Foveal sensitivity changes in retinitis pigmentosa
Abstract:
Loss in foveal sensitivity in retinitis pigmentosa (RP) has been attributed to a decrease in quantal catching ability. Using a psychophysical technique (the probe-flash paradigm), we previously found that the results obtained for six RP patients under light adapted conditions were not consistent with a quantal catch hypothesis. To test further this hypothesis twelve RP patients were examined in dark adapted conditions. Probe thresholds were normal for five patients and increased for seven patients. The decreased quantal catching hypothesis was rejected for six of the seven patients.
Related Concept Videos
Photoreceptors and Visual Pathways
Anatomy of the Eyeball
The Retina
