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Related Concept Videos

Quality Control01:05

Quality Control

Quality control is one of the three cyclical quality assurance activities that help keep a system under statistical control. Typical quality control activities include creating quality control charts, conducting proficiency testing, and documenting and archiving results.
Quality control helps track data, visualize trends, and identify variations, making it easier to detect deviations that may affect the accuracy of an analysis. One way to do this is by generating a quality control chart, which...
Coagulation01:09

Coagulation

The coagulation phase is a critical part of the body's process to prevent blood loss following injury to blood vessels. It involves chemical reactions that form a clot to seal the injured area. The clotting process begins shortly after injury, within 15-20 seconds for severe damage and 1-2 minutes for minor injuries.
During the coagulation phase, clotting factors, or procoagulants, play a vital role in initiating and progressing the coagulation cascade. This cascade is a series of reactions...
Coagulation01:06

Coagulation

Colloidal solids are solid particles suspended in solution. They are usually negatively charged, attracting a compact primary layer of positively charged ions, which attract more counterions to form an electrical double layer. Electrostatic repulsion between the charged double layers prevents the particles from colliding, stabilizing the colloids. These solids are often undesirable because they can contain toxins that are difficult to remove. Coagulation is a technique that helps aggregate and...
Quality Assurance01:19

Quality Assurance

Quality assurance is the overarching term used to describe the activities employed to ensure the proper performance of a system. These activities can be classified into three categories: quality control, quality assessment, and internal corrective measures. Typically, these activities work cyclically: quality control is performed before and during the analysis, while quality assessment occurs during and after the investigation. Internal corrective measures are implemented based on the findings...
Anticoagulant Drugs: Low-Molecular-Weight Heparins01:30

Anticoagulant Drugs: Low-Molecular-Weight Heparins

Hemostasis is a crucial process that prevents excessive blood loss from damaged blood vessels. It involves various mechanisms such as vasoconstriction, platelet adhesion and activation, and fibrin formation. The importance of each mechanism depends on the type of vessel injury. In contrast, thrombosis is the abnormal formation of a blood clot within the blood vessels, leading to potential complications if the clot obstructs blood flow. Thrombosis can be caused by increased coagulability of the...
Introduction to Hemostasis01:05

Introduction to Hemostasis

Hemostasis is a complex physiological process that prevents excessive bleeding when a blood vessel is injured. It's crucial for maintaining the integrity of the circulatory system, as it ensures that our blood remains fluid while still within the vascular network and yet clots to prevent blood loss upon vessel injury.
The three phases of hemostasis involve many clotting factors present in plasma and several substances released by platelets and injured tissue cells. It is a fast, localized, and...

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Related Experiment Video

Updated: Jun 13, 2026

Rapid Point-of-Care Assay of Enoxaparin Anticoagulant Efficacy in Whole Blood
11:17

Rapid Point-of-Care Assay of Enoxaparin Anticoagulant Efficacy in Whole Blood

Published on: October 12, 2012

[POCT in coagulation. Quality assurance].

Michael Spannagl1, A Dick, R Junker

  • 1INSTAND e.V., Düsseldorf.

Hamostaseologie
|May 11, 2010
PubMed
Summary

Point of care testing (POCT) for coagulation requires robust quality assurance, including user education and system controls. Comprehensive quality management is crucial for POCT coagulation systems, even without ideal control materials.

Area of Science:

  • Clinical diagnostics
  • Medical laboratory science
  • Point-of-care testing (POCT)

Context:

  • POCT coagulation systems are increasingly used in routine diagnostics.
  • Existing POCT applications, like blood gas analysis, highlight the need for user education and quality assurance.
  • Comprehensive quality management is not yet established for all POCT coagulation systems.

Purpose:

  • To discuss the varying quality management concepts for different POCT coagulation methods.
  • To emphasize the importance of user education and instrument self-control for total quality assurance.
  • To advocate for implementing comprehensive quality management despite limitations in control materials.

Summary:

  • Quality management for POCT coagulation systems varies based on control material availability and system self-control features.

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A Microfluidic Flow Chamber Model for Platelet Transfusion and Hemostasis Measures Platelet Deposition and Fibrin Formation in Real-time
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A Microfluidic Flow Chamber Model for Platelet Transfusion and Hemostasis Measures Platelet Deposition and Fibrin Formation in Real-time

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The Nijmegen Hemostasis Assay: Simultaneous Fluorogenic Measurement of Thrombin and Plasmin Generation in a Single Well
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A Microfluidic Flow Chamber Model for Platelet Transfusion and Hemostasis Measures Platelet Deposition and Fibrin Formation in Real-time

Published on: February 14, 2017

  • Key components of quality assurance include high-quality manufacturing, user education, instrument self-monitoring, and the use of electronic or liquid control samples.
  • A robust quality management strategy should address pre-analytic, technical, and post-analytic criteria.

    • Impact:

    • Promotes improved accuracy and reliability of POCT coagulation testing.
    • Encourages the development and implementation of standardized quality management protocols for POCT devices.
    • Ensures patient safety and effective clinical decision-making through dependable diagnostic results.