[Thromboelastography/-metry and external quality control. Results of a pilot study]

Area of Science:

• Clinical pathology
• Hemostasis and thrombosis
• Point-of-care testing

Context:

• Thromboelastography/Thromboelastometry (TEG/ROTEM) is crucial for managing acute bleeding in perioperative and intensive care.
• A standardized external quality control for TEG/ROTEM results has been lacking.
• This study addresses the need for quality management in TEG/ROTEM analysis.

Purpose:

• To evaluate the feasibility of external quality assessment for Thromboelastometry (ROTEM) results.
• To assess the reproducibility of ROTEM parameters using lyophilized plasma samples.
• To establish a framework for quality control in near-patient hemostasis testing.

Summary:

• A pilot survey in 2008-2009 integrated into External Quality Assessment Schemes (EQAS) assessed ROTEM results.
• Lyophilized plasma samples were used, demonstrating good reproducibility for clot firmness (A20) and alpha-angle.
• Higher variability was observed for Clotting Time (CT) and Clot Formation Time (CFT), particularly with low fibrinogen levels.

Impact:

• This study demonstrates that ROTEM results can be reliably controlled through external quality schemes.
• Regular participation in external quality assurance can validate TEG/ROTEM as a beneficial technology in emergency settings.
• Improved quality control will enhance the reliability of TEG/ROTEM for acute bleeding management.