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Cellular energy metabolism and regulation.
J M Kelly1, M Summers, H S Park
1Department of Animal and Poultry Science, University of Guelph, ON, Canada.
Journal of Dairy Science
|February 1, 1991
Summary
Lactation increases nutrient demand, altering digestive tissues like the rumen, intestine, and liver. Energy is redirected to ion transport and protein turnover, with potential impacts on muscle metabolism.
Area of Science:
- Animal Physiology
- Metabolic Biochemistry
Background:
- Lactation and growth significantly increase nutrient demands.
- Digestive and metabolic tissues adapt to meet these demands.
Purpose of the Study:
- To investigate metabolic changes in non-mammary tissues during lactation.
- To understand the energy expenditure shifts in response to lactation.
Main Methods:
- Analysis of tissue size changes (rumen, intestine, liver).
- Assessment of energy expenditure on ion transport and protein turnover.
- Evaluation of substrate cycle involvement, including the triacylglycerol fatty acid cycle.
Main Results:
- Rumen, upper intestine, and liver increase in size during lactation.
- Increased energy expenditure observed for Na+,K+ transport and protein turnover.
- Lactation influences specific substrate cycles, notably the triacylglycerol fatty acid cycle.
Conclusions:
- Lactation profoundly impacts digestive and metabolic tissues.
- Further in vivo measurements and mechanistic modeling are needed for non-mammary tissues.