Related Experiment Video
Updated: Jun 13, 2026
04:50
Reproducibility and Harmonization in Research Using Biological Standards: The Example of Platelet Agonist Collagen-Related Peptide
Published on: August 4, 2023
Standardization and omics science: technical and social dimensions are inseparable and demand symmetrical study
Christina Holmes1, Fiona McDonald, Mavis Jones
1Technoscience and Regulation Research Unit, Faculty of Medicine, Dalhousie University, Halifax, Canada.
Omics : a Journal of Integrative Biology
|May 12, 2010
Summary
Standardizing omics science involves both technical and social elements. Flexible, inclusive standard-setting processes enhance legitimacy and practical application in research.
Area of Science:
- Omics science, encompassing genomics, proteomics, and metabolomics.
- High-throughput technologies and their integration.
Background:
- Standardization ensures research quality, interoperability, and product safety.
- Omics science relies on diverse technologies, necessitating robust standards.
- Scientific standards influence the social, ethical, and legal regulatory landscape.
Purpose of the Study:
- To argue that omics science standardization is both technical and social.
- To synthesize social science literature on standardization processes.
- To examine the impact of standardization on scientific practice and legitimacy.
Main Methods:
- Critical synthesis of social science literature.
- Analysis of standardization's practical and social implications.
- Examination of factors influencing standard adoption and legitimacy.
Main Results:
- Standardization requires practical flexibility for diverse scientific sites.
- The creation process and participants impact standard legitimacy and use.
- The standardization process itself bolsters research area legitimacy.
Conclusions:
- Omics science standardization is a socio-technical endeavor.
- Flexible and inclusive approaches are crucial for effective standardization.
- Legitimacy and practical utility are enhanced through thoughtful standard development.
Related Concept Videos
02:02Genomics
Genomics is the science of genomes: it is the study of all the genetic material of an organism. In humans, the genome consists of information carried in 23 pairs of chromosomes in the nucleus, as well as mitochondrial DNA. In genomics, both coding and non-coding DNA is sequenced and analyzed. Genomics allows a better understanding of all living things, their evolution, and their diversity. It has a myriad of uses: for example, to build phylogenetic trees, to improve productivity and...
01:21Tandem Mass Spectrometry
Tandem mass spectrometry is a technique that uses multiple mass analyzers in series to obtain a higher selectivity and reduce chemical noise during analyte detection. Instruments with multiple analyzers separated by an interaction cell enable secondary fragmentation and selected study of the fragment ions.Secondary fragmentations occur in the interaction cell and can be induced by various factors. Fragmentation induced by collision with inert gases, such as N2, Ar, He, etc., is called...
01:30Scientific Nature of Social Psychology
Social psychology is a scientific discipline dedicated to understanding how individuals think, feel, and behave in social contexts. Unlike common sense, which relies on anecdotal experiences and intuition, social psychology employs systematic research and empirical methods to ensure objectivity and reliability. This distinction is fundamental in distinguishing scientifically supported findings from mere speculation.Four fundamental scientific values guide a structured approach to research in...
01:19Methods to Assess Microbial Communities
Microbial communities, comprising bacteria, archaea, and eukaryotic microorganisms, inhabit diverse ecosystems and play crucial roles in environmental and biological processes. Their diversity is defined by three main parameters: species richness (the number of distinct species), species abundance (the relative quantity of each species), and species evenness (how uniformly individual species are distributed in various locations). These factors together shape the structure and ecological balance...
01:23Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches
Biopharmaceutical studies constitute a vital field aiming to enhance drug delivery methods and refine therapeutic approaches, drawing upon diverse interdisciplinary knowledge. In research methodologies, the choice between controlled and non-controlled studies significantly influences the study's reliability and accuracy.
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast, controlled...
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast, controlled...
01:33Proteomics
A proteome is the entire set of proteins that a cell type produces. We can study proteomes using the knowledge of genomes because genes code for mRNAs, and the mRNAs encode proteins. Although mRNA analysis is a step in the right direction, not all mRNAs are translated into proteins.
Proteomics is the study of proteomes' function. It involves the large-scale systematic study of the proteome to denote the protein complement expressed by a genome. Scientist Mark Wilkins coined the term proteomics...
Proteomics is the study of proteomes' function. It involves the large-scale systematic study of the proteome to denote the protein complement expressed by a genome. Scientist Mark Wilkins coined the term proteomics...