Related Experiment Video
Updated: Jun 13, 2026
Measuring and Modeling Contractile Drying in Human Stratum Corneum
Published on: March 1, 2017
A new approach for an estimation of the equilibrium stratum corneum water content
Gorm Krogh Johnsen1, Anne Berit Haugsnes, Orjan G Martinsen
1Department of Physics, University of Oslo, Oslo, Norway. gormj@fys.uio.no
Background/Purpose:
Water content is the most vital parameter governing the overall function of the epidermal stratum corneum (SC). Thus, knowledge of the in vivo absolute water content of the SC is of great interest.
Methods:
We have investigated a non-invasive method for the estimation of in vivo SC water content based on transepidermal water loss measurements combined with desorption studies of SC in vitro, by means of a dynamic vapour sorption setup where relative humidity (RH) and temperature are controlled.
Results:
The SC equilibrium water content of the volar forearm in our study was estimated to be 80+/-7 microg/cm2. The estimate of the water content seems to decrease slightly with increasing ambient RH.
Conclusion:
The estimated water content is a bit lower than what can be expected to be realistic. A calibration against ambient RH is most probably needed if our method is to be applied over a broad range of values of the RH in the ambient air.
More Related Videos
09:32Resolving Water, Proteins, and Lipids from In Vivo Confocal Raman Spectra of Stratum Corneum through a Chemometric Approach
Published on: September 26, 2019
07:21Measurements of Soil Water Potential and Conductivity based on a Simple Evaporation Experiment using a Hydraulic Property Analyzer
Published on: August 9, 2024
