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Related Experiment Video

Updated: Jun 13, 2026

Isolation of Cells with Morphological and Spatial Information from Oral Submucous Fibrosis Samples by Laser Capture Microdissection
05:42

Isolation of Cells with Morphological and Spatial Information from Oral Submucous Fibrosis Samples by Laser Capture Microdissection

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Mohs' micrographic surgery for dermatofibrosarcoma protuberans.

M R Roh1, B Bae, K Y Chung

  • 1Department of Dermatology and Cutaneous Biology Research Institute, Yonsei University College of Medicine, Seoul, Korea.

Clinical and Experimental Dermatology
|May 12, 2010
PubMed
Summary
This summary is machine-generated.

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Mohs micrographic surgery (MMS) offers a low recurrence rate for dermatofibrosarcoma protuberans (DFSP), a rare soft-tissue tumor. This approach may also result in smaller surgical defects compared to traditional wide local excision.

Area of Science:

  • Oncology
  • Dermatology
  • Surgical Pathology

Background:

  • Dermatofibrosarcoma protuberans (DFSP) is a rare soft-tissue neoplasm.
  • DFSP is characterized by a high rate of local recurrence.
  • Mohs micrographic surgery (MMS) shows promise for improved DFSP cure rates.

Purpose of the Study:

  • To evaluate the efficacy of MMS for treating DFSP.
  • To assess recurrence rates of DFSP treated with MMS in a Korean single-institution cohort.
  • To compare MMS outcomes with other DFSP treatment modalities.

Main Methods:

  • Retrospective chart review of 11 DFSP patients treated between 1997 and 2007.
  • Analysis of demographic, tumor, treatment, and follow-up data.
  • Literature review of DFSP treatment methods and recurrence rates.

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Last Updated: Jun 13, 2026

Isolation of Cells with Morphological and Spatial Information from Oral Submucous Fibrosis Samples by Laser Capture Microdissection
05:42

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Published on: August 11, 2023

Establishment of a Clinic-based Biorepository
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Establishment of a Clinic-based Biorepository

Published on: May 29, 2017

Main Results:

  • Eleven DFSP cases (7 female, 4 male; mean age 26.9 years) were analyzed.
  • Complete tumor clearance required an average of 1.8 MMS layers.
  • No recurrences were observed during an average follow-up of 26 months.

Conclusions:

  • MMS treatment for DFSP, both primary and recurrent, yields a low recurrence rate.
  • MMS may offer the advantage of smaller surgical defects compared to wide local excision.
  • MMS is supported as a preferred treatment option for dermatofibrosarcoma protuberans.