Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Cirrhosis I: Introduction01:23

Cirrhosis I: Introduction

Cirrhosis is a chronic, irreversible liver disease characterized by the widespread replacement of healthy liver tissue with fibrotic scar tissue and the formation of regenerative nodules.Etiology of cirrhosisCirrhosis results from sustained liver injury that triggers progressive fibrosis and structural remodeling. The underlying causes are diverse, encompassing common and less frequent clinical conditions. Regardless of the origin, all causes lead to chronic inflammation, hepatocyte loss, and...
Other Disorders of Digestive System01:30

Other Disorders of Digestive System

The gastrointestinal tract is susceptible to various disorders. If the lower esophageal sphincter is damaged, stomach acid can flow back into the esophagus, causing irritation and inflammation of the lining. This condition is called gastroesophageal reflux disease (known as heartburn) and may cause chest pain and difficulty swallowing. In the stomach, prolonged use of nonsteroidal anti-inflammatory drugs like aspirin, chronic alcohol consumption, bacterial infections such as Helicobacter...
Gastritis II: Pathophysiology01:26

Gastritis II: Pathophysiology

The pathophysiology of gastritis begins with the colonization of the stomach lining by Helicobacter pylori (H. pylori). This bacterium spreads mainly via the oral-oral route through saliva or shared utensils, and can also be transmitted in overcrowded or unhygienic environments through contaminated water, despite its brief survival outside the body.ColonizationOnce ingested, H. pylori enters the stomach and begins colonization by navigating through the mucus layer lining the stomach wall. It...
Esophageal Achalasia01:27

Esophageal Achalasia

Esophageal achalasia is a chronic neurogenic disorder characterized by impaired relaxation of the lower esophageal sphincter (LES) and absent or ineffective peristalsis in the distal esophagus. This leads to a functional obstruction without a physical blockage, despite significant disruption of esophageal motility.EtiologyAchalasia is caused by degeneration of the myenteric (Auerbach's) plexus, specifically the loss of inhibitory ganglion cells that produce vasoactive intestinal peptide (VIP)...
Gastritis-II: Pathophysiology01:17

Gastritis-II: Pathophysiology

Gastritis is marked by disruption of the mucosal barrier that usually protects the stomach tissue from digestive juices and manifests in acute and chronic forms.
In acute gastritis, the gastric mucosa becomes swollen and red and undergoes superficial erosion. Superficial ulceration may lead to bleeding.
In chronic gastritis, persistent or repeated insults lead to chronic inflammatory changes and, eventually, thinning or atrophy of the gastric tissue.
Gastritis can stem from various causes, each...
Rheumatic Heart Disease I: Introduction01:23

Rheumatic Heart Disease I: Introduction

Rheumatic heart disease or RHD is a chronic condition that results from rheumatic fever, causing permanent damage to the heart valves.Etiology and Risk FactorsIt primarily arises from rheumatic fever, an inflammatory disease that can develop after untreated or inadequately treated group A streptococcal (GAS) pharyngitis. Streptococcus spreads through direct contact with oral or respiratory secretions. While the bacteria are the causative agents, factors like malnutrition, overcrowding, poor...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Characteristics of JIA-associated uveitis at the age of transition.

Pediatric rheumatology online journal·2026
Same author

Predictors of hypogammaglobulinemia during rituximab maintenance therapy in rheumatoid arthritis: A 12-year longitudinal multi-center study.

Seminars in arthritis and rheumatism·2018
Same author

A large national cohort of French patients with chronic recurrent multifocal osteitis.

Arthritis & rheumatology (Hoboken, N.J.)·2014
Same author

Prevalence and predictors of small intestinal bacterial overgrowth in systemic sclerosis patients with gastrointestinal symptoms.

Clinical and experimental rheumatology·2014
Same author

Individual site-specific bone mineral density gain in normocalcemic primary hyperparathyroidism.

Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·2014
Same author

[The minute structure of the macula region in connection with function tests in tapetoretinal degeneration].

A.M.A. archives of ophthalmology·2014
Same journal

Renal function and venous thromboembolic diseases.

Journal des maladies vasculaires·2016
Same journal

[Ankle-brachial index screening for peripheral artery disease in high cardiovascular risk patients. Prospective observational study of 370 asymptomatic patients at high cardiovascular risk].

Journal des maladies vasculaires·2016
Same journal

[Erratum to "When to worry about before a vascular chronic leg ulcer?" [J. Mal. Vasc. 41 (2016) 307-314]].

Journal des maladies vasculaires·2016
Same journal

[Deep venous thrombosis of the upper limb in a violin player: The "bow syndrome"].

Journal des maladies vasculaires·2016
Same journal

[Economic consequences of biological monitoring and medical complications of injectable anticoagulants in France].

Journal des maladies vasculaires·2016
Same journal

[Vitamin K antagonist, direct oral anticoagulants: Where is the truth?]

Journal des maladies vasculaires·2016
See all related articles

Related Experiment Video

Updated: Jun 13, 2026

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease
04:44

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease

Published on: June 16, 2020

[Watermelon stomach in systemic sclerosis].

K Laoubi1, Y Allanore, S Chaussade

  • 1Service de rhumatologie A, hôpital Cochin, université Paris Descartes, 27, rue du Faubourg-Saint-Jacques, 75014 Paris, France.

Journal Des Maladies Vasculaires
|May 12, 2010
PubMed
Summary
This summary is machine-generated.

Systemic sclerosis (SSc) can affect the digestive tract, leading to rare complications like gastric antral vascular ectasia (GAVE). Early recognition and treatment of GAVE are crucial for managing anemia in SSc patients.

More Related Videos

Application of Ultrasound and Shear Wave Elastography Imaging in a Rat Model of NAFLD/NASH
07:13

Application of Ultrasound and Shear Wave Elastography Imaging in a Rat Model of NAFLD/NASH

Published on: April 20, 2021

Related Experiment Videos

Last Updated: Jun 13, 2026

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease
04:44

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease

Published on: June 16, 2020

Application of Ultrasound and Shear Wave Elastography Imaging in a Rat Model of NAFLD/NASH
07:13

Application of Ultrasound and Shear Wave Elastography Imaging in a Rat Model of NAFLD/NASH

Published on: April 20, 2021

Area of Science:

  • Gastroenterology
  • Rheumatology
  • Vascular Medicine

Background:

  • Systemic sclerosis (SSc) is a connective tissue disease with frequent gastrointestinal (GI) manifestations.
  • GI involvement affects up to 90% of SSc patients, commonly involving the esophagus.

Observation:

  • Gastric antral vascular ectasia (GAVE), or watermelon stomach, is a rare SSc complication.
  • GAVE involves dilated capillaries and potential thrombi beneath the gastric mucosa.
  • This condition is an expression of SSc-related microvasculopathy.

Findings:

  • The precise prevalence of GAVE in SSc is unknown but appears low.
  • GAVE is a significant, though infrequent, cause of anemia in SSc patients.
  • Specific local treatments for GAVE are generally effective.

Implications:

  • Clinicians must be aware of GAVE as a potential cause of anemia in SSc.
  • Timely diagnosis and targeted treatment of GAVE are essential for patient management.
  • Despite treatment efficacy, recurrent GAVE events are common in SSc.