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Acquired noncompaction associated with coronary heart disease and myopathy

Josef Finsterer1, Claudia Stöllberger, Elisabeth Bonner

  • 1Krankenanstalt Rudolfstiftung, Vienna, Austria, Europe. fipaps@yahoo.de

Heart & Lung : the Journal of Critical Care
|May 12, 2010
PubMed

Insights

This case study reveals acquired left ventricular hypertrabeculation (LVHT) in a patient with neuromuscular disease. LVHT may be an adaptive response in impaired myocardium.

Area of Science:

  • Cardiology
  • Neurology
  • Genetics

Background:

  • A 77-year-old male with extensive cardiovascular history presented with worsening heart failure.
  • Transthoracic echocardiography revealed left ventricular hypertrabeculation (LVHT), a finding absent in prior investigations.

Observation:

  • The patient exhibited symptoms suggestive of a metabolic myopathy, including ptosis, madarosis, hearing loss, muscle pain, absent reflexes, and gait ataxia.
  • Elevated creatine kinase levels, with normal troponin-T, further supported a myopathic process.

Findings:

  • Autopsy confirmed severe coronary heart disease and LVHT in the left ventricular apex.
  • The absence of LVHT in previous echocardiograms indicated an acquired condition.

Implications:

  • This case suggests that LVHT can be acquired, particularly in the context of neuromuscular diseases.
  • LVHT might represent an adaptive mechanism in response to myocardial impairment.

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