Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Focusing of Light in the Eye

Focusing of Light in the Eye

Light rays enter the eye through the cornea, a transparent dome-shaped tissue that is the eye's outermost layer. The cornea bends or refracts, light rays traveling to the pupil. The shape of the cornea determines how much of the light is bent and whether the image will be focused correctly on the retina at the back of the eye. Once the light has passed through both refraction layers, it converges into a single focal point onto a small area. This is where photoreceptors start transforming...

Open Angle Glaucoma: Treatment

Open Angle Glaucoma: Treatment

In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...

Angle Closure Glaucoma: Treatment

Angle Closure Glaucoma: Treatment

Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Unaided reading speed in pseudophakic patients after emmetropic monofocal intraocular lens implantation.

Eye (London, England)·2025

Same author

Reply : Incidence and factors for pseudoaccommodation after monofocal lens implantation: the Monofocal Extended Range of Vision study.

Journal of cataract and refractive surgery·2024

Same author

Incidence and factors for pseudoaccommodation after monofocal lens implantation: the Monofocal Extended Range of Vision study.

Journal of cataract and refractive surgery·2023

Same author

Comparison of Anterior Corneal Aberrometry, Keratometry and Pupil Size with Scheimpflug Tomography and Ray Tracing Aberrometer.

Vision (Basel, Switzerland)·2022

Same author

Vitamin A deficiency presenting with fungal keratitis and bilateral corneal perforations.

BMJ case reports·2022

Same author

Two new words.

Journal of cataract and refractive surgery·2021

Search research articles

Related Experiment Video

Updated: Jun 13, 2026

Correction of Presbyopia by Monocular Bi-Aspheric Ablation Profile

Published on: September 20, 2024

Pilot study of new focus-shift accommodating intraocular lens.

Georgia Cleary¹, David J Spalton, John Marshall

¹Department of Ophthalmology, St. Thomas' Hospital, London, United Kingdom.

Journal of Cataract and Refractive Surgery

|May 12, 2010

Summary

The OPAL-A accommodating intraocular lens (IOL) demonstrated minimal objective accommodation and axial shift. Near vision was primarily due to depth of focus, not true pseudophakic accommodation.

More Related Videos

Rotating the Intraocular Lens to Prevent Posterior Capsular Opacification in Cataract Surgeries

Rotating the Intraocular Lens to Prevent Posterior Capsular Opacification in Cataract Surgeries

Published on: July 7, 2023

Related Experiment Videos

Last Updated: Jun 13, 2026

Correction of Presbyopia by Monocular Bi-Aspheric Ablation Profile

Published on: September 20, 2024

Rotating the Intraocular Lens to Prevent Posterior Capsular Opacification in Cataract Surgeries

Rotating the Intraocular Lens to Prevent Posterior Capsular Opacification in Cataract Surgeries

Published on: July 7, 2023

Area of Science:

Ophthalmology
Biomedical Engineering
Optics

Background:

Cataract surgery often involves intraocular lens (IOL) implantation to restore vision.
Accommodating IOLs aim to mimic the natural eye's ability to focus at different distances.
The OPAL-A is a focus-shift accommodating IOL designed to provide a range of vision.

Purpose of the Study:

To evaluate the visual and accommodative performance of the OPAL-A focus-shift accommodating intraocular lens (IOL).

Main Methods:

Unilateral phacoemulsification and accommodating IOL implantation were performed.
Patients were followed for 6 months post-surgery.
Visual acuities (CDVA, DCNVA), objective and subjective accommodation amplitudes, and IOL movement were measured using autorefractors, push-up tests, defocus curves, and anterior segment optical coherence tomography.

Main Results:

Mean corrected distance visual acuity (CDVA) remained stable (around -0.05 to -0.08).
Mean distance-corrected near visual acuity (DCNVA) was approximately 0.31-0.34.
Objective accommodation amplitude was low (0.10-0.36 D), while subjective accommodation varied (0.90-2.79 D).
Physiological IOL shift was minimal (45.2 microm), but pilocarpine-stimulated shift reached 306 microm at 6 months.

Conclusions:

The OPAL-A accommodating IOL showed clinically insignificant objective accommodation and forward axial shift.
Observed near visual performance is likely attributable to the depth of focus rather than true pseudophakic accommodation.