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Published on: July 14, 2023
Nutritional status and clinical characteristics in children with juvenile rheumatoid arthritis
Shou-Ting Shin1, Hsin-Hui Yu, Li-Chieh Wang
1Department of Pediatrics, Far Eastern Memorial Hospital, Taipei, Taiwan.
Insights
Juvenile rheumatoid arthritis (JRA) in Taiwanese children is linked to impaired nutritional status, with lower Body Mass Index (BMI) observed in affected children compared to healthy peers.
Area of Science:
- Pediatrics
- Rheumatology
- Nutrition Science
Background:
- Juvenile rheumatoid arthritis (JRA) is a chronic inflammatory condition affecting children.
- Understanding the clinical profile and nutritional status of JRA patients is crucial for effective management.
Purpose of the Study:
- To investigate the clinical characteristics of JRA in Taiwanese children.
- To assess the nutritional status, specifically Body Mass Index (BMI), of JRA patients.
- To compare the nutritional status of JRA patients with a healthy control group.
Main Methods:
- A cohort of 53 Taiwanese children diagnosed with JRA was studied.
- Clinical data, including disease subtype and patient characteristics, were recorded.
- Body Mass Index (BMI) was measured and compared between JRA patients and 75 age-matched healthy controls.
Main Results:
- Inflammation markers were elevated in the systemic JRA group.
- JRA patients exhibited significantly lower BMI compared to controls (p = 0.006).
- This BMI difference was more pronounced in males, children over 4 years old, and those with oligoarticular onset JRA.
Conclusions:
- Nutritional status is frequently compromised in children with JRA.
- Lower BMI in JRA patients, particularly males and those with later onset, highlights nutritional concerns.
- Oligoarticular onset JRA was the most prevalent subtype in this Taiwanese cohort.
Background/Purpose:
The aim of the study was to investigate the clinical characteristics and nutritional status of juvenile rheumatoid arthritis (JRA) in Taiwanese children.
Methods:
Fifty-three patients were included in this study. The disease subtype and patient characteristics were recorded. Body mass index (BMI) was determined. Seventy-five healthy age-matched children served as a control group.
Results:
The inflammation parameters, including white blood cell count, platelet count, C-reactive protein, and erythrocyte sedimentation rate, were elevated in the systemic group. The BMI level of the JRA group was significantly lower than the control group (p = 0.006), especially in the male patients (p = 0.016) and when the patient age was greater than 4 (p = 0.011). The patients with oligoarticular onset JRA had significantly lower BMI compared with the healthy control group (p = 0.012).
Conclusion:
Nutritional status is often impaired in patients with JRA. The BMI of the JRA patients was lower than that of age-matched healthy children, especially in the male group, and when disease onset age was greater than 4. In our unselected sample, the most affected disease subtype was oligoarticular onset JRA.
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