Related Experiment Video
Updated: Jun 13, 2026

Studying Murine Small Bowel Mechanosensing of Luminal Particulates
Published on: March 18, 2022
Contrast-enhanced MRI of the small bowel in Crohn's disease
1Department of Radiology, University of Chicago, Chicago, IL, USA. jkoommen1@gmail.com
Abstract:
Recently, magnetic resonance imaging has emerged as a valuable tool in evaluation of small bowel Crohn's disease. MRI provides several advantages to other imaging modalities, including the lack of ionizing radiation, multiplanar capability, and functional information. Intravenous contrast administration is a routine portion of MR enterography protocol, and aids in detection of disease extent, extramural complications such as fistula and abscess, and assessment of activity. Additionally, promising techniques such as dynamic contrast-enhanced MRI may provide quantitative measures to assess bowel perfusion, which may enhance evaluation of disease activity. This article will provide an overview of the technical aspects of contrast-enhanced MR enterography, describe common pathologic findings involving the small bowel in Crohn's disease, summarize its role in determination of activity with an emphasis on endoscopic and histologic correlation, and compare its efficacy with other imaging modalities.
Insights
Magnetic resonance imaging (MRI) is a valuable tool for evaluating small bowel Crohn's disease, offering advantages like no radiation. Contrast-enhanced MR enterography helps detect disease extent, complications, and activity, aiding in patient management.
Area of Science:
- Radiology
- Gastroenterology
- Medical Imaging
Background:
- Small bowel Crohn's disease evaluation traditionally relies on various imaging modalities.
- Magnetic resonance imaging (MRI) offers unique advantages over conventional methods.
Purpose of the Study:
- To provide an overview of contrast-enhanced MR enterography for small bowel Crohn's disease.
- To correlate imaging findings with endoscopic and histologic data.
- To compare MRI efficacy with other imaging modalities.
Main Methods:
- Review of technical aspects of contrast-enhanced MR enterography.
- Description of common pathologic findings in small bowel Crohn's disease on MRI.
- Emphasis on dynamic contrast-enhanced MRI for quantitative perfusion assessment.
Main Results:
- MRI aids in detecting disease extent, extramural complications (fistula, abscess), and assessing disease activity.
- Dynamic contrast-enhanced MRI shows promise for quantitative bowel perfusion evaluation.
- Correlations with endoscopic and histologic findings are crucial for accurate activity assessment.
Conclusions:
- Contrast-enhanced MR enterography is a key imaging tool for small bowel Crohn's disease.
- MRI provides comprehensive information on disease extent, complications, and activity.
- Further research into advanced MRI techniques can enhance diagnostic capabilities.
Related Concept Videos
Inflammatory Bowel Disease II: Crohn's Disease
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by transmural...
Inflammatory Bowel Disease III: Crohn's Disease
Imaging Studies III: Gastrointestinal Motility Studies and Virtual Colonoscopy
Radionuclide Testing
Radionuclide testing is a sophisticated medical technique for assessing gastrointestinal motility. It focuses on gastric emptying and colonic transit time. Radioactive markers track the movement of food through the digestive system, providing insights into gastrointestinal disorders.
In gastric emptying studies, a meal's liquid and solid...
Lower GI Series: Barium Enema
Procedure Details
The examination begins by inserting a lubricated rectal tube into the patient's rectum to administer a radiopaque barium solution. The barium flow is carefully...
Inflammatory Bowel Disease IV: Clinical Manifestations
Histology of the Small Intestine
The intestinal lining features transverse folds called circular folds, each housing fingerlike projections known as intestinal villi. These villi are covered by a layer of simple columnar epithelium, also referred to as...
