Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Cancer Prevention02:59

Cancer Prevention

Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...
Cancer Prevention02:59

Cancer Prevention

Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...
Preventive Healthcare Services01:30

Preventive Healthcare Services

Preventive healthcare services keep people healthy via frequent check-ups, screening, and counseling. They primarily aid in disease prevention rather than treating an acute or chronic illness. Preventive treatment also keeps individuals productive and energetic, allowing them to work well into their retirement years. Examples of preventive care services include:
What is Cancer?02:12

What is Cancer?

Cells and tissues must meticulously coordinate their activities for the normal functioning of the human body. Therefore, they exhibit socially responsible behavior - resting, growing, dividing, differentiating, or dying - for the organism’s benefit. Cancer arises when cells divide uncontrollably and invade other tissues or organs.
Although people have known about cancer for centuries, it was only in 1761 that Giovanni Morgagni of Padua performed a detailed autopsy of patients who died from...
What is Cancer?02:12

What is Cancer?

Cells and tissues must meticulously coordinate their activities for the normal functioning of the human body. Therefore, they exhibit socially responsible behavior - resting, growing, dividing, differentiating, or dying - for the organism’s benefit. Cancer arises when cells divide uncontrollably and invade other tissues or organs.
Although people have known about cancer for centuries, it was only in 1761 that Giovanni Morgagni of Padua performed a detailed autopsy of patients who died from...
Cancer-Critical Genes II: Tumor Suppressor Genes01:05

Cancer-Critical Genes II: Tumor Suppressor Genes

Genes usually encode proteins necessary for the proper functioning of a healthy cell. Mutations can often cause changes to the gene expression pattern, thereby altering the phenotype.
When the function of certain critical genes, especially those involved in cell cycle regulation and cell growth signaling cascades, gets disrupted, it upsets the cell cycle progression. Such cells with unchecked cell cycles start proliferating uncontrollably and eventually develop into tumors.
Such genes that act...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Screening for breast cancer: what truly is the benefit?

Canadian journal of public health = Revue canadienne de sante publique·2014
Same author

Etiologic study vis-à-vis intervention study.

European journal of epidemiology·2010
Same author

Ignoring critique, attacking the critic.

European journal of epidemiology·2010
Same author

Early lung cancer action project: annual screening using single-slice helical CT.

Annals of the New York Academy of Sciences·2002
Same author

The modern scientific physician: 7. Theory of medicine.

CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne·2002
Same author

The modern scientific physician: 8. Educational preparation.

CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne·2002
Same journal

Different risks, same causes: educational attainment influences when, not from what, we die.

European journal of epidemiology·2026
Same journal

Loneliness around the world: patterns, predictors, and well-being implications.

European journal of epidemiology·2026
Same journal

Cohort profile: Swiss personalized health network cohort consortium.

European journal of epidemiology·2026
Same journal

The SINTER study: a recall-by-genotype design with multidimensional musculoskeletal phenotyping across internal-medicine outpatient clinics.

European journal of epidemiology·2026
Same journal

SARS-CoV-2 infection as a trigger of type 2 diabetes in adults: a population-based cohort study in Sweden using a double negative control design.

European journal of epidemiology·2026
Same journal

Cohort profile: transformative research on equity and social determinants to uplift resilience and empower LGBTQ+ health in China (TREASURE).

European journal of epidemiology·2026
See all related articles

Related Experiment Video

Updated: Jun 13, 2026

Screening Ion Channels in Cancer Cells
06:19

Screening Ion Channels in Cancer Cells

Published on: June 16, 2023

Screening for a cancer: thinking before rethinking.

O S Miettinen1

  • 1Department of Epidemiology, Biostatistics and Occupational Health, McGill University, 1020 Pine Avenue West, Montreal, QC, H2A 1A2, Canada. olli.miettinen@mcgill.ca

European Journal of Epidemiology
|May 12, 2010
PubMed
Summary
This summary is machine-generated.

Rethinking cancer screening requires recognizing its clinical nature, not just epidemiological data. Clinicians, not epidemiologists, should lead discussions on cancer screening practices and research.

More Related Videos

Genome-Wide CRISPR Screen for Unveiling Radiosensitive and Radioresistant Genes
08:32

Genome-Wide CRISPR Screen for Unveiling Radiosensitive and Radioresistant Genes

Published on: May 23, 2025

Related Experiment Videos

Last Updated: Jun 13, 2026

Screening Ion Channels in Cancer Cells
06:19

Screening Ion Channels in Cancer Cells

Published on: June 16, 2023

Genome-Wide CRISPR Screen for Unveiling Radiosensitive and Radioresistant Genes
08:32

Genome-Wide CRISPR Screen for Unveiling Radiosensitive and Radioresistant Genes

Published on: May 23, 2025

Area of Science:

  • Medical Research
  • Clinical Practice
  • Public Health Policy

Background:

  • Recent evidence-based questioning of breast and prostate cancer screening premises by Esserman et al. has been widely accepted.
  • This questioning, while using epidemiological data, lacked adequate critical thinking and revealed misunderstandings in current screening research.
  • The premises of cancer screening, early diagnosis, and patient counseling are fundamentally clinical in nature.

Purpose of the Study:

  • To advocate for a fundamental rethinking of cancer screening methodologies.
  • To differentiate the roles of epidemiologists and clinicians in cancer screening research and practice.
  • To emphasize the clinical underpinnings of cancer screening over purely epidemiological interpretations.

Main Methods:

  • Critical analysis of existing epidemiological approaches to cancer screening research.
  • Review of contemporary understanding of diagnostic and prognostic premises in cancer screening.
  • Examination of the interpretation of evidence used in cancer screening studies.

Main Results:

  • Current epidemiological approaches to cancer screening are based on flawed interpretations and misunderstandings.
  • Cancer screening and early diagnosis are inherently clinical processes requiring clinical expertise.
  • Epidemiologists should focus on community-level medicine, not presume expertise in clinical screening issues.

Conclusions:

  • A paradigm shift is needed, recognizing clinical expertise as primary in cancer screening.
  • Clinicians and clinical researchers should lead cancer screening discussions, disregarding external public health or epidemiological directives.
  • This reevaluation is critical, as exemplified by recent breast cancer screening recommendations and public reactions.