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Updated: Jun 13, 2026

Murine Fetal Echocardiography
Published on: February 15, 2013
[Abnormal chords of the left ventricle]
Insights
Abnormal chords of the left ventricle (ACLV) have an unclear prognostic significance. Their impact on cardiovascular disease depends on connective tissue dysplasia and associated complications, not just presence.
Area of Science:
- Cardiology
- Pathophysiology
- Echocardiography
Background:
- The prognostic significance of abnormal chords of the left ventricle (ACLV) is ambiguous in medical literature.
- The role of ACLV in the pathogenesis of cardiovascular disease remains unclear.
Purpose of the Study:
- To clarify the prognostic significance of ACLV.
- To understand the factors influencing ACLV prognosis and their role in cardiovascular disease.
Main Methods:
- Literature data analysis.
- Review of studies evaluating prognostic factors associated with ACLV.
Main Results:
- ACLV prognosis is influenced by connective tissue dysplasia, number/location of anomalous chords, and hemodynamic/arrhythmic complications.
- ACLV can be mistaken for other pathologies or mask significant findings during echocardiography.
Conclusions:
- The mere presence of ACLV is less critical than associated factors for prognosis.
- Accurate identification of anomalous intracavitary structures is crucial to avoid diagnostic errors in echocardiography.
Abstract:
The analysis of literature data has showed that evaluation of prognostic significance of abnormal chords of the left ventricle (ACLV) is ambiguous. It remains an open question on the participation of ACLV in the pathogenesis of cardiovascular disease. Obviously, the prognosis of ACLV is determined not so much by the fact of its existence, as degree of connective tissue dysplasia, the number and topic of anomalous chords, the presence of hemodynamic and/or arrhythmic complications. Identification and verification of the anomalous intracavitary structures are important, because they often serve as potential sources of echodiagnostic mistakes, for they can mask more important pathological findings.
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