Related Experiment Video
Updated: Jun 13, 2026

Application of DNA Fingerprinting using the D1S80 Locus in Lab Classes
Published on: July 17, 2021
[Polymorphism of paraoxonase (PON-1) gene in Slavonic part of Kharkiv population]
Abstract:
Polymorphism of PON-1 gene in 192 position of amino acid sequence of enzyme paraoxonase 1 related to the synthesis of allozymes R or Q was studied. For this research we used blood samples of 109 donors (men/women: 78/31; 84 Ukrainian, 25 Russian)--habitants of Kharkiv. Frequency of Q and R alleles were pQ = 0.67, pR = 0.33. Distinctions of allele frequencies among Ukrainians and Russians and also among men and women were not significant. Distributing of genotype frequencies in the Slavonic population of Kharkiv corresponds to panmictic population.
Related Concept Videos
Pharmacogenetics of Drug Transporters: P-Glycoprotein and Solute Carrier Transporters
Pharmacogenetics of Phase I Enzymes: Cytochrome P450 Isozymes
Pharmacogenetic Phenotypes: Alterations in Pharmacokinetics, Drug Targets and Biologic Milieu
Principles of Pharmacogenetics: Types of Genetic Variants
Pharmacogenetics of Drug Metabolism: Overview
Pharmacogenetics of Drug Targets: β₂-Adrenergic Receptors, Apo E, Thymidylate Synthase
