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Related Experiment Video

Updated: Jun 13, 2026

In vitro Assessment of Aortic Regurgitation Using Four-Dimensional Flow Magnetic Resonance Imaging
11:16

In vitro Assessment of Aortic Regurgitation Using Four-Dimensional Flow Magnetic Resonance Imaging

Published on: February 25, 2022

Analysis of flow patterns in a patient-specific aortic dissection model.

Z Cheng1, F P P Tan, C V Riga

  • 1Department of Chemical Engineering, Imperial College London, London, UK.

Journal of Biomechanical Engineering
|May 13, 2010
PubMed
Summary

Aortic dissection involves disturbed blood flow, with 80% entering the false lumen, potentially worsening aortic dilatation. High wall shear stress near the tear may increase its expansion risk.

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Area of Science:

  • Cardiovascular Science
  • Biomedical Engineering
  • Fluid Dynamics

Background:

  • Aortic dissection, a critical thoracic aorta event, often leads to aneurysmal dilatation in 25% of Type B cases.
  • Understanding flow dynamics in dissected aortas is crucial for predicting disease progression and guiding treatment.

Purpose of the Study:

  • To investigate the intricate blood flow phenomena within a patient-specific dissected thoracic aorta.
  • To analyze morphological features and flow patterns contributing to aortic dilatation and tear propagation.

Main Methods:

  • Patient-specific computational fluid dynamics (CFD) simulations using computed tomography (CT) imaging.
  • Employed a transitional turbulence model (Menter's hybrid k-epsilon/k-omega SST) in ANSYS CFX.
  • Incorporated non-Newtonian blood behavior for enhanced simulation accuracy.

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Experimental Investigation of Secondary Flow Structures Downstream of a Model Type IV Stent Failure in a 180° Curved Artery Test Section

Published on: July 19, 2016

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Last Updated: Jun 13, 2026

In vitro Assessment of Aortic Regurgitation Using Four-Dimensional Flow Magnetic Resonance Imaging
11:16

In vitro Assessment of Aortic Regurgitation Using Four-Dimensional Flow Magnetic Resonance Imaging

Published on: February 25, 2022

Experimental Investigation of Secondary Flow Structures Downstream of a Model Type IV Stent Failure in a 180° Curved Artery Test Section
11:00

Experimental Investigation of Secondary Flow Structures Downstream of a Model Type IV Stent Failure in a 180° Curved Artery Test Section

Published on: July 19, 2016

Main Results:

  • Dissected aorta exhibits highly disturbed flow with significant recirculation, and approximately 80% of flow enters the false lumen.
  • High wall shear stress (WSS) observed around the tear on the true lumen wall, potentially promoting tear expansion.
  • Maximum turbulence intensity reached 70% during midsystolic deceleration; non-Newtonian effects slightly altered WSS and turbulence intensity.

Conclusions:

  • Turbulent flow and significant false lumen flow are key characteristics of dissected aortas, driving dilatation.
  • Elevated WSS at the tear site is a critical factor for dissection progression and warrants further investigation.
  • CFD modeling, especially with transitional turbulence, provides valuable insights into the hemodynamics of aortic dissection.