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Updated: Jun 13, 2026

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Extraction of Venom and Venom Gland Microdissections from Spiders for Proteomic and Transcriptomic Analyses
Published on: November 3, 2014
Black widow spider envenomation in pregnancy
Michael D Wolfe1, Orrin Myers, E Martin Caravati
1Department of Obstetrics and Gynecology, Division of Maternal Fetal Medicine, University of New Mexico Health Sciences Center, Albuquerque, NM 87131-0001, USA. mdwolfe@salud.unm.edu
Summary
Black widow spider bites during pregnancy are rare. While pregnant women experienced more medical outcomes than non-pregnant women, no pregnancy losses were documented, suggesting favorable short-term outcomes.
Area of Science:
- Toxicology
- Obstetrics
- Epidemiology
Background:
- Limited data exist on black widow spider envenomation during pregnancy.
- Understanding treatment and outcomes is crucial for maternal and fetal health.
Purpose of the Study:
- To evaluate clinical effects and medical outcomes of black widow spider envenomation in pregnant versus non-pregnant women.
- To compare treatment differences between these groups.
Main Methods:
- Observational study using data from the American Association of Poison Control Centers (2003-2007).
- Analysis of 12,640 reported black widow spider envenomations, focusing on reproductive-age women (15-45 years).
Main Results:
- Of 3,194 reproductive-age women, 97 were pregnant.
- No significant differences in recommended or administered treatments were found between pregnant and non-pregnant women.
- Pregnant women had higher rates of minor, moderate, or major outcomes and increased healthcare facility utilization (release or admission).
- No pregnancy losses were documented.
Conclusions:
- Black widow spider envenomation in pregnancy is uncommon.
- Short-term outcomes for pregnant women appear favorable, despite increased healthcare encounters.
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