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Related Concept Videos

Oral Hypoglycemic Agents: α-Glucosidase Inhibitors01:19

Oral Hypoglycemic Agents: α-Glucosidase Inhibitors

α-glucosidase inhibitors, including acarbose (Precose), miglitol (Glyset), and voglibose (Voglib) (primarily available in Asia), are drugs that control blood sugar levels by delaying the digestion of starch and disaccharides. They achieve this by inhibiting α-glucosidase enzymes in the intestine, which slow the absorption of carbohydrates in the intestine, which in turn leads to a prolonged release of the glucoregulatory hormone GLP-1 from intestinal L-cells.
Acarbose and miglitol are typically...

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Elucidating &#946;-1,3-Glucanase and Peroxidase Physicochemical Properties of Wheat Cell Wall Defense Mechanism Against Diuraphis noxia Infestation
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Interactions between xylanase and glucanase in maize-soy-based diets for broilers.

A J Cowieson1, M R Bedford, V Ravindran

  • 1AB Vista Feed Ingredients, Marlborough, SN8 4AN, UK. aaron.cowieson@abagri.com

British Poultry Science
|May 13, 2010
PubMed
Summary

Adding xylanase and glucanase enzymes to broiler diets improves feed conversion and nutrient digestibility. A combination of both enzymes showed the best results, but caution is advised when reducing added fat.

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Area of Science:

  • Animal Science
  • Poultry Nutrition
  • Enzyme Technology

Background:

  • Maize/soy-based diets are common for broiler chickens.
  • Enzymes like xylanase and glucanase can improve nutrient utilization.
  • Reducing dietary energy density by removing fat can negatively impact broiler performance.

Purpose of the Study:

  • To evaluate the effects of different doses of xylanase and glucanase on broiler performance and nutrient digestibility.
  • To determine the optimal combination and dosage of these enzymes in maize/soy-based diets.
  • To assess the impact of enzyme supplementation when dietary energy is reduced.

Main Methods:

  • A total of 960 male broiler chickens were used in growth and digestibility trials.
  • Ten dietary treatments were tested, including positive and negative controls, and diets with individual or combined enzyme supplementation.
  • Feed conversion ratio (FCR) and ileal nutrient digestibility were measured at 21 and 42 days.

Main Results:

  • The negative control diet (lower energy density) resulted in poorer FCR and lower energy digestibility compared to the positive control.
  • Supplementation with both xylanase and glucanase improved FCR and ileal nutrient digestibility.
  • A sub-additive effect was observed with combined enzyme use, with the best performance at specific dosages of xylanase and glucanase.

Conclusions:

  • Reducing added fat in broiler diets to account for enzyme effects can be detrimental to performance.
  • A combination of xylanase and glucanase is beneficial for maximizing enzyme response in maize/soy diets.
  • Moderation in fat removal is recommended when using non-starch polysaccharide degrading enzymes in starter diets.