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Updated: Jun 13, 2026

Evaluation of Colorectal Cancer Risk and Prevalence by Stool DNA Integrity Detection

Evaluation of Colorectal Cancer Risk and Prevalence by Stool DNA Integrity Detection

Published on: June 8, 2020

Screening for colorectal cancer.

Gail Waldby¹, John J Ryan

¹Royal C. Johnson Veterans Memorial Medical Center, Sioux Falls, SD, USA.

South Dakota Medicine : the Journal of the South Dakota State Medical Association

|May 14, 2010

Summary

Cancer screening detects early-stage cancers in asymptomatic individuals. Colorectal cancer screening is recommended for those over 50 with a life expectancy over five years, aiding early detection and treatment.

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Last Updated: Jun 13, 2026

Evaluation of Colorectal Cancer Risk and Prevalence by Stool DNA Integrity Detection

Evaluation of Colorectal Cancer Risk and Prevalence by Stool DNA Integrity Detection

Published on: June 8, 2020

Area of Science:

Oncology
Preventive Medicine
Gastroenterology

Background:

Cancer screening aims to detect unsuspected cancers in asymptomatic populations.
Screening is effective when tests are safe, diseases are prevalent, and false positives are minimal.
Early diagnosis through screening can prolong lifespan.

Observation:

Colorectal cancer is the third-most common cancer in Western countries.
Many colorectal cancers develop from precancerous lesions like adenomatous polyps.
Screening facilitates early detection of both cancer and precancerous polyps.

Findings:

Colorectal cancer screening enables earlier detection of cancers and polyps.
It allows for timely and potentially curative therapeutic interventions.
Screening is indicated for individuals with a life expectancy >5 years, generally under 75.

Implications:

Early detection of colorectal cancer through screening improves patient outcomes.
Identifying and removing precancerous polyps prevents cancer development.
Widespread screening can reduce colorectal cancer mortality rates.