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Updated: Jun 13, 2026

Portal Vein Injection of Colorectal Cancer Organoids to Study the Liver Metastasis Stroma

Portal Vein Injection of Colorectal Cancer Organoids to Study the Liver Metastasis Stroma

Published on: September 3, 2021

Lung carcinosarcoma.

M J Vidal Losada¹, V Bernal Monterde, B Amores Arriaga

¹Servicio de Oncología Médica, Hospital Clínico Universitario Lozano Blesa, Zaragoza, Spain. vidalmar80@hotmail.com

Clinical & Translational Oncology : Official Publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico

|May 14, 2010

Summary

This summary is machine-generated.

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Rous Sarcoma Virus (RSV) and Cancer

Rous Sarcoma Virus (RSV) and Cancer

Rous Sarcoma virus or RSV was discovered by F. Peyton Rous in the year 1911 as a filterable transmissible agent that could cause tumors in chickens. He won a Nobel Prize for this discovery in 1966. His experiments clearly demonstrated that some cancers could be caused by infectious agents and led to the discovery of many more cancer-causing viruses in animals as well as humans.
RSV is a retrovirus that contains two copies of a plus-strand RNA genome. Its genome consists of four main open...

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Lung carcinosarcoma, a rare aggressive tumor, requires surgical intervention as chemotherapy and radiotherapy are ineffective. This case highlights diagnostic challenges and clinical outcomes in patients with this rare lung cancer.

Area of Science:

Oncology
Pulmonology
Pathology

Background:

Lung carcinosarcoma is a rare, high-grade malignant neoplasm characterized by both epithelial and mesenchymal components.
This aggressive tumor predominantly affects male smokers, typically between the fifth and eighth decades of life.

Observation:

The study details the diagnostic process for a patient diagnosed with lung carcinosarcoma.
The patient presented with multiple paraneoplastic syndromes, complicating the diagnosis and management.

Findings:

Chemotherapy and radiotherapy demonstrate limited efficacy against lung carcinosarcoma.
Surgery is identified as the primary treatment modality for this rare lung malignancy.
The prognosis for lung carcinosarcoma is poor, with a 6-month survival rate of approximately 27%.

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Last Updated: Jun 13, 2026

Portal Vein Injection of Colorectal Cancer Organoids to Study the Liver Metastasis Stroma

Portal Vein Injection of Colorectal Cancer Organoids to Study the Liver Metastasis Stroma

Published on: September 3, 2021

Implications:

This case underscores the diagnostic complexities associated with lung carcinosarcoma, particularly when accompanied by paraneoplastic syndromes.
The findings reinforce the critical role of surgical resection in managing this aggressive tumor.
Further research into effective therapeutic strategies for lung carcinosarcoma is warranted given the poor prognosis.