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Related Concept Videos

Fungal Group Zygomycota01:29

Fungal Group Zygomycota

Zygomycota, previously classified as a distinct fungal group, are primarily terrestrial, saprophytic molds that play a crucial role as decomposers. Recent phylogenetic studies have revealed that these fungi are now divided into two major clades — Mucoromycota, which includes many symbiotic species, and Zoopagomycota, which primarily consists of parasitic and pathogenic fungi. These groups exhibit distinct ecological roles and reproductive strategies while sharing key structural and...
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Skin Diseases and Disorders

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Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
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Fungal Phylum Microsporidia

Microsporidia are a group of obligate intracellular fungi that were initially classified as protists but were later reclassified based on phylogenetic, molecular, and structural evidence linking them to the Chytridiomycota. These unicellular, non-motile organisms are highly specialized parasites that infect a wide range of animal hosts, including humans. They have evolved extensive genomic and metabolic reductions, making them highly dependent on their hosts for survival.Morphology and Genomic...
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Pulmonary Tuberculosis III

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Cryptococcal Meningitis01:27

Cryptococcal Meningitis

Cryptococcal meningitis is a life-threatening opportunistic infection predominantly associated with HIV/AIDS, accounting for over 100,000 deaths annually worldwide. However, it also affects individuals with other forms of immunosuppression, including those undergoing immunosuppressive therapy, organ transplant recipients, patients with innate immunodeficiencies, and individuals with hematological disorders. The infection is caused mainly by Cryptococcus neoformans and Cryptococcus gattii,...
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Related Experiment Video

Updated: Jun 13, 2026

Toxoplasma gondii Cyst Wall Formation in Activated Bone Marrow-derived Macrophages and Bradyzoite Conditions
09:56

Toxoplasma gondii Cyst Wall Formation in Activated Bone Marrow-derived Macrophages and Bradyzoite Conditions

Published on: August 12, 2010

Blastomycosis.

Jeannina A Smith1, Carol A Kauffman

  • 1Division of Infectious Diseases, University of Michigan Medical School, Veterans Affairs Ann Arbor Healthcare System, 2215 Fuller Road, Ann Arbor, MI 48105, USA.

Proceedings of the American Thoracic Society
|May 14, 2010
PubMed
Summary

Blastomycosis is a fungal infection endemic to North America, often causing mild or asymptomatic respiratory illness. Severe cases can lead to acute respiratory distress syndrome (ARDS), necessitating updated clinical management guidelines.

Area of Science:

  • Mycology
  • Infectious Diseases
  • Pulmonology

Background:

  • Blastomycosis is an endemic fungal infection prevalent in North America.
  • It commonly manifests as acute or chronic pneumonia, with cutaneous lesions as a frequent extrapulmonary sign.
  • Most infections are asymptomatic or present with mild, undiagnosed respiratory symptoms.

Purpose of the Study:

  • To provide an overview of blastomycosis, including its epidemiology, clinical manifestations, and diagnostic challenges.
  • To highlight the availability of new diagnostic tools and updated clinical guidelines for managing blastomycosis.
  • To emphasize the importance of accurate diagnosis and treatment for severe cases.

Main Methods:

  • Review of epidemiological data on blastomycosis distribution in North America.

Related Experiment Videos

Last Updated: Jun 13, 2026

Toxoplasma gondii Cyst Wall Formation in Activated Bone Marrow-derived Macrophages and Bradyzoite Conditions
09:56

Toxoplasma gondii Cyst Wall Formation in Activated Bone Marrow-derived Macrophages and Bradyzoite Conditions

Published on: August 12, 2010

  • Description of clinical presentations, ranging from asymptomatic infection to severe pulmonary disease and ARDS.
  • Evaluation of current diagnostic methods, including antigen tests, antibody assays, and culture.
  • Reference to updated Infectious Diseases Society of America guidelines for blastomycosis management.

    • Main Results:

    • Blastomycosis is geographically concentrated in specific regions of North America.
    • The majority of infections are subclinical, but severe pulmonary disease and ARDS can occur with high mortality.
    • Current diagnostic tests have limitations; culture remains the gold standard.
    • New urinary antigen tests are available but lack specificity.

    Conclusions:

    • Accurate diagnosis of blastomycosis remains challenging due to non-specific symptoms and diagnostic tests.
    • Prompt recognition and management, guided by updated clinical protocols, are crucial for improving outcomes.
    • Further research into more specific diagnostic markers for blastomycosis is warranted.