Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Cryptococcal Meningitis01:27

Cryptococcal Meningitis

Cryptococcal meningitis is a life-threatening opportunistic infection predominantly associated with HIV/AIDS, accounting for over 100,000 deaths annually worldwide. However, it also affects individuals with other forms of immunosuppression, including those undergoing immunosuppressive therapy, organ transplant recipients, patients with innate immunodeficiencies, and individuals with hematological disorders. The infection is caused mainly by Cryptococcus neoformans and Cryptococcus gattii,...
Fungal Phylum Ascomycota01:28

Fungal Phylum Ascomycota

Phylum Ascomycota, a major division within the subkingdom Dikarya, comprises a diverse range of fungal species, including both unicellular yeasts and filamentous molds such as Aspergillus and Penicillium. These fungi thrive in a variety of habitats, from aquatic ecosystems to terrestrial environments, playing crucial ecological and economic roles.Morphology and ReproductionThe defining characteristic of Ascomycetes, commonly referred to as sac fungi, is the ascus—a sac-like structure that...
Pulmonary Tuberculosis I01:29

Pulmonary Tuberculosis I

Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Pneumonia I: Introduction01:30

Pneumonia I: Introduction

Pneumonia is an acute respiratory infection that targets the lungs, specifically the alveoli. These tiny air sacs, essential for oxygen exchange, become engorged with pus and fluid, severely hindering breathing, decreasing oxygen absorption, and causing significant pain and discomfort during respiration.
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
Pneumonia I: Introduction01:29

Pneumonia I: Introduction

Pneumonia is an infection of the lower respiratory tract that leads to inflammation of the lung parenchyma, often resulting in the accumulation of inflammatory exudate in the alveoli and airways. Unlike the watery, low-protein fluid exudate in pulmonary edema, the exudate in this case is a thick fluid rich in immune cells, proteins, and debris produced during infection and inflammation.This impairs gas exchange and can lead to consolidation of lung tissue. The infection may be caused by a...
Transmission-based Precautions II: Airborne and Protective Environment01:25

Transmission-based Precautions II: Airborne and Protective Environment

Transmission-based precautions are for patients infected or suspected to be infected (or colonized) with organisms posing a significant risk to others. The transmission precautions include airborne and protective environment precautions.
Airborne precautions:
Use airborne precautions when treating patients known or suspected to have diseases that spread through the air—for example, tuberculosis or measles. These organisms are present in smaller droplets expelled by an infected person and...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Outcomes of Lung Transplantation From Asphyxiation Donors: Reassessing Hypoxic Injury and Implications for Donation After Circulatory Death.

Interdisciplinary cardiovascular and thoracic surgery·2026
Same author

Immune gene correlation networks differentiate both chronic lung allograft dysfunction and survival.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons·2026
Same author

Reframing surgical decision-making when treating severe pulmonary hypertension: Beyond the binary of lungs alone vs combined heart-lung transplantation.

The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation·2025
Same author

Revisiting optimal static lung preservation techniques in an era when machine perfusion is transforming organ recovery: thermoregulation is still an important concept.

Journal of thoracic disease·2025
Same author

Beyond the incision: Integrating mechanical circulatory support and less-invasive approaches in lung transplantation.

The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation·2025
Same author

Characterization of Spirometric Response to Standard-of-care Treatment in Lung Allograft Recipients With Bronchiolitis Obliterans and the Utility of Spirometric Criteria for Rescue Therapy: Implications for the Design of Risk-stratified Clinical Trials.

Transplantation·2025

Related Experiment Video

Updated: Jun 13, 2026

Detection of Invasive Pulmonary Aspergillosis in Haematological Malignancy Patients by using Lateral-flow Technology
08:01

Detection of Invasive Pulmonary Aspergillosis in Haematological Malignancy Patients by using Lateral-flow Technology

Published on: March 22, 2012

Aspergillus infections in the critically ill.

Radek Dutkiewicz1, Chadi A Hage

  • 1Pulmonary Critical Care Medicine, Indiana University School of Medicine, Indianapolis, Indiana, USA.

Proceedings of the American Thoracic Society
|May 14, 2010
PubMed
Summary

Invasive aspergillosis is increasing in critically ill patients without malignancy. Early diagnosis and sensitive tools are crucial for managing this serious fungal infection.

Area of Science:

  • Infectious Diseases
  • Critical Care Medicine
  • Mycology

Background:

  • Invasive aspergillosis is a severe complication in immunocompromised patients.
  • Rising incidence observed in critically ill patients without malignancy due to increased immunosuppression and survival.

Purpose of the Study:

  • To discuss the epidemiology, risk factors, and clinical spectrum of invasive aspergillosis in critically ill non-malignant patients.
  • To present diagnostic methods and treatment recommendations.
  • To emphasize early diagnosis using sensitive tools.

Main Methods:

  • Review of current literature and clinical data on invasive aspergillosis in critically ill non-malignant patients.
  • Analysis of epidemiological trends, risk factors, and clinical presentations.

More Related Videos

Histological Quantification to Determine Lung Fungal Burden in Experimental Aspergillosis
09:52

Histological Quantification to Determine Lung Fungal Burden in Experimental Aspergillosis

Published on: March 9, 2018

Related Experiment Videos

Last Updated: Jun 13, 2026

Detection of Invasive Pulmonary Aspergillosis in Haematological Malignancy Patients by using Lateral-flow Technology
08:01

Detection of Invasive Pulmonary Aspergillosis in Haematological Malignancy Patients by using Lateral-flow Technology

Published on: March 22, 2012

Histological Quantification to Determine Lung Fungal Burden in Experimental Aspergillosis
09:52

Histological Quantification to Determine Lung Fungal Burden in Experimental Aspergillosis

Published on: March 9, 2018

  • Evaluation of diagnostic strategies and therapeutic approaches.

    • Main Results:

    • Invasive aspergillosis is a growing concern in critically ill patients without hematologic malignancies.
    • Identification of specific risk factors and clinical manifestations in this population.
    • Highlighting the need for advanced diagnostic techniques for timely detection.

    Conclusions:

    • Critically ill patients without malignancy are increasingly susceptible to invasive aspergillosis.
    • Prompt diagnosis and appropriate treatment are essential for improving outcomes.
    • The use of novel and sensitive diagnostic tools is paramount for effective management.