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Updated: Jun 13, 2026

Deep Proteome Profiling by Isobaric Labeling, Extensive Liquid Chromatography, Mass Spectrometry, and Software-assisted Quantification
Published on: November 15, 2017
[The significance of proteomics in public health]
Rosa Victoria Pando-Robles1, Humberto Lanz-Mendoza
1Centro de Investigación sobre Enfermedades Infecciosas, Instituto Nacional de Salud Pública, Cuernavaca, Morelos, México.
Abstract:
The proteome is defined as the entirety of proteins expressed by a genome in a given time under specific physiological conditions. In an organism, the cells contain the same genome; however, they express different proteins in response to a specific micro-environment. Proteomics is responsible for the study of proteomes, using a wide range of methodological techniques. Actually, proteomics is a key tool in health research because it has made possible systematic analysis of hundreds of proteins in clinical samples with the promise of discovering new protein biomarkers for different disease conditions. Finally, proteomic strategy is a technology well-suited to provide a better understanding of systems biology and human health.
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