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[Paroxysmal cold hemoglobinuria: only in the textbooks?]
L Escoda1, A Pereira, A Graena
1Servicio de Hematología Clínica, Hospital Clínic i Provincial, Barcelona.
Medicina Clinica
|March 23, 1991
Summary
Paroxysmal cold hemoglobinuria (PCH), a rare condition, can cause episodic red blood cell destruction triggered by cold. Early diagnosis and penicillin treatment are crucial for managing this syphilis-associated hemolytic anemia.
Area of Science:
- Hematology
- Immunology
- Infectious Diseases
Background:
- Paroxysmal cold hemoglobinuria (PCH) is a rare autoimmune hemolytic anemia.
- It is characterized by the destruction of red blood cells upon exposure to cold.
- Historically associated with syphilis, PCH is now exceptionally rare.