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Related Experiment Video

Updated: Jun 13, 2026

Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents
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Retinal function in patients with serpiginous choroiditis: a microperimetry study.

Elisabetta Pilotto1, Stela Vujosevic, Vuga Ana Grgic

  • 1Department of Ophthalmology, University of Padova, via Giustiniani 2, Padua, Italy. elisabetta.pilotto@unipd.it

Graefe'S Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Fur Klinische Und Experimentelle Ophthalmologie
|May 14, 2010
PubMed
Summary

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Microperimetry reveals significant visual impairment in serpiginous choroiditis (SC) patients, with reduced retinal sensitivity found even in seemingly healthy areas, indicating broader functional loss.

Area of Science:

  • Ophthalmology
  • Retinal Diseases
  • Visual Neuroscience

Background:

  • Serpiginous choroiditis (SC) is a rare inflammatory condition affecting the choroid and retina.
  • Understanding the functional impact of SC on visual perception is crucial for patient management.

Purpose of the Study:

  • To investigate the fixation patterns and retinal sensitivity in patients diagnosed with serpiginous choroiditis.
  • To correlate microperimetric findings with disease activity and lesion morphology.

Main Methods:

  • Evaluation of 28 eyes from 14 patients with SC using best-corrected visual acuity, fundus imaging, and angiography.
  • Microperimetry was employed to assess fixation stability and retinal sensitivity.
  • Correlation of functional data with morphological findings from color fundus photography, fundus autofluorescence, and fluorescein and indocyanine green angiography.

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Multifocal Electroretinograms

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Last Updated: Jun 13, 2026

Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents
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Published on: February 15, 2022

Multifocal Electroretinograms
16:49

Multifocal Electroretinograms

Published on: December 4, 2011

Main Results:

  • A majority of eyes (57%) exhibited central fixation, with a significant proportion (39%) showing eccentric fixation.
  • Fixation stability varied, with 64% demonstrating stable fixation.
  • Retinal sensitivity deficits, including dense and relative scotomas, were observed at lesion margins and in areas not morphologically affected by the disease.

Conclusions:

  • Microperimetry provides valuable insights into the visual impairment caused by serpiginous choroiditis.
  • Reduced retinal sensitivity in apparently healthy retinal areas suggests a more extensive functional involvement than visible on imaging alone.
  • These findings highlight the importance of functional assessment in understanding the full impact of SC on vision.