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3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache
10:39

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache

Published on: June 2, 2014

Is migraine a disease?

Pietro Cortelli1, G Pierangeli, P Montagna

  • 1Dipartimento di Scienze Neurologiche, Center for the Study of Headaches, Alma Mater Studiorum-Università di Bologna, Bologna, Italy. pietro.cortelli@unibo.it

Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology
|May 14, 2010
PubMed
Summary
This summary is machine-generated.

Migraine attacks, initially adaptive brain responses, can become chronic pain diseases if maladaptive mechanisms develop. Early recognition and treatment are crucial to prevent this transformation.

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Area of Science:

  • Neuroscience
  • Pathophysiology
  • Behavioral Science

Background:

  • Migraine attacks are characterized by pain, autonomic symptoms, and sickness behavior, suggesting a brain response to stressors.
  • This response may be a genetically determined, adaptive mechanism orchestrated by a threatened brain.

Purpose of the Study:

  • To re-evaluate the nature of migraine attacks from a disease perspective.
  • To explore the transition of migraine attacks from a normal response to a chronic pain state.
  • To emphasize the importance of early intervention in preventing chronic migraine.

Main Methods:

  • Conceptual analysis of migraine pathophysiology.
  • Allostatic perspective on the development of chronic pain.
  • Review of current understanding of migraine as a brain dysfunction.

Main Results:

  • Migraine attacks may not be a disease but a reversible brain dysfunction.
  • Repeated attacks can lead to maladaptive mechanisms, resulting in chronic brain pain (chronic migraine).
  • Migraine can be viewed as a symptom of underlying syndromes rather than solely a headache attack.

Conclusions:

  • Migraine attacks represent a complex brain response that can transition into a chronic disease state.
  • Early identification and treatment of factors leading to maladaptive mechanisms are essential.
  • Migraine should be considered not only as a headache but also as a potential symptom of broader neurological syndromes.